Monkey Brain-derived neurotrophic factor(BDNF) ELISA kit

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产品详情

产品描述：

CUSABIO猴脑源性神经营养因子（BDNF）酶联免疫检测试剂盒（货号：CSB-EL002655RH），采用双抗体夹心ELISA法实现定量分析，适用于检测血清、血浆及组织匀浆样本中BDNF的蛋白表达水平，检测灵敏度为0.78 ng/mL，线性范围为0.78-50 ng/mL。BDNF是神经营养因子家族的重要成员，在神经元存活、突触可塑性及神经再生等过程中发挥关键作用，其表达水平变化常被用于神经退行性疾病、抑郁症及认知功能相关机制的科学研究。本试剂盒通过高特异性抗体对目标蛋白进行捕获与检测，操作流程标准化，可稳定分析不同来源样本的BDNF浓度差异，为神经生物学基础研究、疾病动物模型评估或药物干预效果验证等科研场景提供可靠数据支持。该产品严格限定于科学研究用途，不涉及任何临床诊断相关应用。
别名：

BDNFBrain-derived neurotrophic factor ELISA kit; BDNF) [Cleaved into: BDNF precursor form ELISA kit; ProBDNF)] ELISA kit; Fragment ELISA kit
缩写：

BDNF
Uniprot No.：

Q06225
种属：

Monkey
样本类型：

serum, plasma, tissue homogenates
检测范围：

0.78 ng/mL-50 ng/mL
灵敏度：

0.195 ng/mL
反应时间：

1-5h
样本体积：

50-100ul
检测波长：

450 nm
研究领域：

Cardiovascular
测定原理：

quantitative
测定方法：

Sandwich

精密度：

Intra-assay Precision (Precision within an assay): CV%<8%
Three samples of known concentration were tested twenty times on one plate to assess.
Inter-assay Precision (Precision between assays): CV%<10%
Three samples of known concentration were tested in twenty assays to assess.

标准曲线：

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

功能：

Important signaling molecule that activates signaling cascades downstream of NTRK2. During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability.; Important signaling molecule that activates signaling cascades downstream of NTRK2. Activates signaling cascades via the heterodimeric receptor formed by NGFR and SORCS2. Signaling via NGFR and SORCS2 plays a role in synaptic plasticity and long-term depression (LTD). Binding to NGFR and SORCS2 promotes neuronal apoptosis. Promotes neuronal growth cone collapse.
亚细胞定位：

Secreted.; [BDNF precursor form]: Secreted.
蛋白家族：

NGF-beta family
数据库链接：

STRING: 9544.ENSMMUP00000011324

UniGene: Mmu.3380