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Mouse C-X-C motif chemokine 3(CXCL3) ELISA kit

  • 中文名称:
    小鼠C-X-C趋化因子3(CXCL3)酶联免疫试剂盒
  • 货号:
    CSB-EL006249MO
  • 规格:
    96T/48T
  • 价格:
    ¥3600/¥2500
  • 其他:

产品详情

  • 产品描述:
    CUSABIO小鼠C-X-C趋化因子3(CXCL3)酶联免疫吸附检测试剂盒(货号:CSB-EL006249MO),基于双抗体夹心法原理,可定量检测血清、血浆及组织匀浆样本中CXCL3的浓度。CXCL3属于趋化因子家族,在炎症反应、免疫细胞迁移及组织修复中发挥重要作用,其表达水平与感染性疾病、自身免疫紊乱及肿瘤微环境调控密切相关。试剂盒检测灵敏度高,线性范围为7.8-500 pg/mL,可精准覆盖小鼠模型中CXCL3的生理及病理浓度变化。实验操作简便,适用于基础科研领域,例如通过分析CXCL3在小鼠感染模型、自身免疫性疾病模型或肿瘤移植模型中的动态变化,探究其与中性粒细胞募集、血管生成或免疫逃逸等过程的关联机制。试剂盒配套标准品、预包被特异性抗体及优化反应体系,支持科研人员高效开展CXCL3相关分子机制研究及生物标志物探索。
  • 别名:
    Cxcl3 ELISA Kit; Dcip1 ELISA Kit; Gm1960C-X-C motif chemokine 3 ELISA Kit; Dendritic cell inflammatory protein 1 ELISA Kit
  • 缩写:
  • Uniprot No.:
  • 种属:
    Mus musculus (Mouse)
  • 样本类型:
    serum, plasma, tissue homogenates
  • 检测范围:
    7.8 pg/mL-500 pg/mL
  • 灵敏度:
    1.56 pg/mL
  • 反应时间:
    1-5h
  • 样本体积:
    50-100ul
  • 检测波长:
    450 nm
  • 研究领域:
    Immunology
  • 测定原理:
    quantitative
  • 测定方法:
    Sandwich
  • 精密度:

  • 线性度:

  • 回收率:

  • 标准曲线:

  • 数据处理:
  • 货期:
    3-5 working days

产品评价

靶点详情

  • 功能:
    Ligand for CXCR2. Has chemotactic activity for neutrophils. May play a role in inflammation and exert its effects on endothelial cells in an autocrine fashion.
  • 基因功能参考文献:
    1. The studies revealed that, although overall structural and oligomerization features of CXCL3 and CXCL2 are similar, prominent differences were observed in their surface characteristics, thus implicating a functional divergence. PMID: 28928065
    2. these results have indicated that CXCL3 is a novel adipokine that facilitates adipogenesis in an autocrine and/or a paracrine manner through induction of c/ebpb and c/ebpd. PMID: 27512010
    3. Tis21 induces migration of cerebellar granule neuron precursor cells through Cxcl3, which may represent a novel target for medulloblastoma therapy PMID: 23115191
    4. DCIP-1 interacts with chemokine CXCR2 and mediates human neutrophil chemotaxis, consistent with its role during the early proinflammatory phase of dendritic cell maturation. PMID: 14764687
  • 亚细胞定位:
    Secreted.
  • 蛋白家族:
    Intercrine alpha (chemokine CxC) family
  • 数据库链接: