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中文名称：小鼠雌二醇(E2)酶联免疫试剂盒
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货号：CSB-E05109m
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规格：96T/48T
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价格：￥3200/￥2500
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其他：
产品详情
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产品描述：小鼠雌二醇(E2)酶联免疫试剂盒（CSB-E05109m）为竞争法ELISA试剂盒，定量检测血清、血浆样本中的E2含量。雌二醇（E2）是小鼠体内重要的雌激素，负责调节女性特征、附属性器官成熟和月经-排卵周期，促进乳腺导管系统产生。研究显示，E2在促进小鼠肺腺癌进展中起关键作用，其机制可能与E2受体ERβ信号通路相关，而IL-6可能通过下调ERβ信号通路抑制E2促进肺腺癌进展。试剂盒检测范围为50 pg/ml-1200 pg/ml，灵敏度为40 pg/ml。适用于基础科研场景，例如探究生殖周期中激素动态变化、评估药物或环境因素对内分泌系统的影响，或用于代谢性疾病模型中激素水平与病理进程的关联性分析本品仅用于科研，不用于临床诊断，产品具体参数及操作步骤详见产品说明书。
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别名：N/A
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缩写：E2
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种属：Mus musculus (Mouse)
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样本类型：serum, plasma
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检测范围：50 pg/ml-1200 pg/ml.
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灵敏度：40 pg/ml.
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反应时间：1-5h
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样本体积：50-100ul
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检测波长：450 nm
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研究领域：Signal Transduction
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测定原理：quantitative
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测定方法：Competitive
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精密度：
Intra-assay Precision (Precision within an assay): CV%<15%
Three samples of known concentration were tested twenty times on one plate to assess.
Inter-assay Precision (Precision between assays): CV%<15%
Three samples of known concentration were tested in twenty assays to assess.
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标准曲线：
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
pg/ml
OD1
OD2
Average
0
2.185
2.254
2.220
50
1.176
1.167
1.172
120
0.743
0.718
0.730
250
0.518
0.529
0.524
500
0.340
0.321
0.331
1200
0.177
0.168
0.172
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数据处理：
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货期：3-5 working days
引用文献
- Afamin Ameliorates Testosterone Propionate (TP)-Induced Oxidative Stress and Mitochondrial Damage in Human Ovarian Granulosa Tumor Cells (KGN) by Upregulating the Expression of SIRT1 YL Ma, ZW Li, Z Wang, AJ Yang,Molecular Biology,2024
- Circulating Interleukin-6 Mediates PM2.5-Induced Ovarian Injury by Suppressing the PPARγ Pathway Y Chen, J Zhang, T Zhang, Y Wu, Y Xi, T Wu, M Li, Y Li,Research,2024
- Mesenchymal stem cell-derived extracellular vesicles therapy for primary ovarian insufficiency: a systematic review and meta-analysis of pre-clinical studies SR Firouzabadi, I Mohammadi, K Ghafourian,Journal of Ovarian Research,2024
- High-fat diet-induced L-saccharopine accumulation inhibits estradiol synthesis and damages oocyte quality by disturbing mitochondrial homeostasis J Wen, Y Feng, L Xue, S Yuan, Q Chen, A Luo,Gut Microbes,2024
- DCAF2 is essential for the development of uterine epithelia and mouse fertility M Yang, K Wang, L Zhang, H Zhang,Frontiers in Cell and Developmental Biology,2024
- Integrated Single-Cell and Spatial Transcriptomics Reveal Microenvironment Disruptions by Androgen in Mouse Ovary M Luo, X Yang, M Zhou, J Zhang, B Yu, H Lian, J Ye,iScience,2024
- The effect of norepinephrine on ovarian dysfunction by mediating ferroptosis in mice model hanqing hong, C Xiao, lichun Weng, Q Wang, D Lai,bioRxiv,2024
- Mesenchymal stem cell-derived apoptotic vesicles ameliorate impaired ovarian folliculogenesis in polycystic ovary syndrome and ovarian aging by targeting WNT signaling Y Fu,Theranostics,2024
- Spatiotemporal transcriptomic changes of human ovarian aging and the regulatory role of FOXP1 M Wu,Nature aging,2024
- Preserving Fertility: Minimizing Ovarian Lymphatic Drainage Disruption in Gynecological Cancer Surgeries D Chen,/,2024
- Rfamide-Related Peptide-3 (RFRP-3) Receptor Gene is Expressed in Mouse Ovarian Granulosa Cells: Potential Role of RFRP-3 in Steroidogenesis and Apoptosis X Guo,/,2023
- Ovary-derived Decellularized Extracellular Matrix-based Bioink for Fabricating 3D Primary Ovarian Cells-laden Structures for Mouse Ovarian Failure Correction J Zheng,International Journal of Bioprinting,2023
- Preventive effect of swim bladder hydrolysates on cyclophosphamide‐induced ovarian injury in mice E Ge,journal of obstetrics and gynaecology research,2023
- The Effects of Paeonia lactiflora Pall. and Astragalus Membranaceus Single Extracts on Bone Metabolic Profile in Ovariectomized Mice H Liu,/,2024
- Vomeronasal Receptors Associated with Circulating Estrogen Processing Chemosensory Cues in Semi-Aquatic Mammals W Xie,International journal of molecular sciences,2023
- Gestational cadmium exposure disrupts fetal liver development via repressing estrogen biosynthesis in placental trophoblasts YT Fu,Food and chemical toxicology,2023
- Human Pluripotent Stem Cell–Mesenchymal Stem Cell-Derived Exosomes Promote Ovarian Granulosa Cell Proliferation and Attenuate Cell Apoptosis Induced by Cyclophosphamide in a POI-like Mouse Model L Zhang,Molecules,2023
- Increased cellular senescence in doxorubicin-induced murine ovarian injury: effect of senolytics Y Gao,GeroScience,2023
- The Effect of an Extract and Fractions of Date Pits on Some Plasma Constituents, Reproductive Hormones, and Testicular Histology in Male Mice M Al Za'abi,The Scientific World Journal,2022
- Ahi1 regulates serotonin production by the GR/ERβ/TPH2 pathway involving sexual differences in depressive behaviors B Wang,Cell communication and signaling,2022
- Senotherapy Protects against Cisplatin-Induced Ovarian Injury by Removing Senescent Cells and Alleviating DNA Damage D Du,Oxidative medicine and cellular longevity,2022
- Anti-Müllerian Hormone Inhibits FSH-Induced Cumulus Oocyte Complex In Vitro Maturation and Cumulus Expansion in Mice X Yu,Animals,2022
- A Docosahexaenoic Acid Derivative (N-Benzyl Docosahexaenamide) as a Potential Therapeutic Candidate for Treatment of Ovarian Injury in the Mouse Model L Guo,Molecules,2022
- Estrogen signaling regulates seasonal changes of the prostate in wild ground squirrels (Spermophilus dauricus) H Zhang,The Journal of steroid biochemistry and molecular biology,2022
- Cyanidin-3-O-glucoside ameliorates cadmium induced uterine epithelium proliferation in mice Dacheng Yang,Journal of Hazardous Materials,2021
- Overaccumulation of fat caused rapid reproductive senescence but not loss of ovarian reserve in ob/ob mice ML Mollah,Journal of the Endocrine Society,2020
- Synergistic effect of Huyang Yangkun Formula and embryonic stem cells on 4-vinylcyclohexene diepoxide induced premature ovarian insufficiency in mice M Li,Chinese Medicine,2020
- Potential of Auraptene in Improvement of Oocyte Maturation, Fertilization Rate, and Inflammation in Polycystic Ovary Syndrome Mouse Model M Abizadeh,Reproductive Sciences,2020
- Receptor Binding Inhibitor Suppresses Carcinogenesis of Cervical Cancer by Depressing Levels of FSHR and ERβ in Mice Gong Z,Anti-Cancer Agents in Medicinal Chemistry,2019
- Hashimoto’s thyroiditis impairs embryo implantation by compromising endometrial morphology and receptivity markers in euthyroid mice Wu Z, et al,Reproductive Biology and Endocrinology,2019
- Therapeutic effects of human umbilical cord mesenchymal stem cell-derived microvesicles on premature ovarian insufficiency in mice Z Yang, et al,Stem Cell Research & Therapy,2019
- FSH receptor binding inhibitor restrains ovarian cancer through down-regulating expression levels of FSHR and ERβ in mice Zhuandi G, et al,Gene,2018
- Determine the Role of FSH Receptor Binding Inhibitor in Regulating Ovarian Follicles Development and Expression of FSHR and ERα in Mice Luju Lai.et al,BioMed Research International,2018
- In vivo toxicity and genotoxicity of beauvericin and enniatins. Combined approach to study in vivo toxicity and genotoxicity of mycotoxins beauvericin (BEA) and enniatin B (ENNB) Francesca Maranghi.et al,EFSA Journal,2018
- FSH receptor binding inhibitor restrains follicular development and possibly attenuates carcinogenesis of ovarian cancer through down-regulating expression levels of FSHR and ERβ in normal ovarian tissues GongZhuandi.et al,Gene,2018
- Silica nanoparticle exposure inducing granulosa cell apoptosis and follicular atresia in female Balb/c mice Liu J.et al,Environ Sci Pollut Res Int,2017
- Methoxsalen supplementation attenuates bone loss and inflammatory response in ovariectomized mice. Ham JR.et al,Chem Biol Interact.,2017
- Bu Shen Tiao Chong recipe restores diminished ovary reserve through the BDNF pathway. Xia T.et al,J Assist Reprod Genet.,2016
- Sex hormone affects the severity of non-alcoholic steatohepatitis through the MyD88-dependent IL-6 signaling pathway Xin G et al,Exp Biol Med (Maywood),2015
产品评价
平均分:
样品类型：血清
样品信息：小鼠
稀释比：其他 稀释五倍
产品评价： 标曲不用自己配这一点很方便，实验结果两次基本趋势相同，标曲较好
By 李老师
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最新研究进展：stradiol（E2）是一种雌激素，是雌性动物体内最主要的雌激素之一。E2在女性中起着重要的生殖和生理功能，如卵巢发育、月经周期、性腺功能等。E2的最新研究显示，它与许多疾病的发生和发展有关，包括乳腺癌、子宫内膜癌、骨质疏松、自身免疫病等。目前已有很多研究致力于研究E2的生物学功能和在疾病治疗方面的应用。
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