Rat 8-Hydroxy-desoxyguanosine,8-OHdG ELISA Kit
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中文名称:
大鼠8羟基脱氧鸟苷(8-OHdG)酶联免疫试剂盒
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货号:
CSB-E10526r
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规格:
96T/48T
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价格:
¥3900/¥2500
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其他:
引用文献
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MA Za'abi,Biomolecules,2021
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β-Sitosterol attenuates liver injury in a rat model of chronic alcohol intake
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Shihao Chen, et al,Ecotoxicology and Environmental Safety,2019
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Galangin Activates Nrf2 Signaling and Attenuates Oxidative Damage, Inflammation, and Apoptosis in a Rat Model of Cyclophosphamide-Induced Hepatotoxicity
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Amelioration of fenitrothion induced oxidative DNA damage and inactivation of caspase-3 in the brain and spleen tissues of male rats by N-acetylcysteine
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Hossein TaheriChadorneshin, et al,Sport Sciences for Health,2018
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靶点详情
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最新研究进展:
8-OHdG是DNA氧化损伤的标志物,最新研究发现,其与肺癌、肝癌、结直肠癌、卵巢癌等多种癌症的发生和发展有关。研究人员通过对癌症患者和对照组进行对比分析,发现8-OHdG的水平在癌症患者中明显升高,因此可以作为肿瘤的生物标志物之一。
此外,8-OHdG的水平还可以反映环境暴露和生活方式对人体DNA的影响。最新研究表明,8-OHdG的水平与吸烟、饮酒、肥胖、缺乏锻炼等不良生活习惯有关。因此,8-OHdG的测量可以用作评估生活方式和环境暴露的生物标志物。
另外,一些研究还表明,8-OHdG可能与一些神经退行性疾病的发生和发展有关,包括帕金森病和阿尔茨海默病。在这些疾病中,氧化应激和DNA氧化损伤可能是致病机制之一,而8-OHdG的测量可以用作评估疾病进展和治疗效果的生物标志物。
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