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中文名称:大鼠I型胶原α1链 (COL1A1)酶联免疫试剂盒
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货号:CSB-E12732r
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规格:96T/48T
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价格:¥3800/¥2500
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其他:
产品详情
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产品描述:CUSABIO大鼠I型胶原α1链(COL1A1)酶联免疫检测试剂盒(货号:CSB-E12732r),采用夹心法原理实现定量分析,能够精准检测血清、血浆及组织匀浆样本中COL1A1的表达水平。COL1A1是构成I型胶原蛋白的核心组分,广泛分布于骨骼、皮肤等结缔组织中,其表达异常与纤维化疾病、创伤修复及组织重塑等病理生理过程密切相关。试剂盒检测灵敏度达0.156 ng/mL,线性范围为0.156-10 ng/mL,适用于低浓度样本的稳定检测。通过预包被特异性抗体的微孔板与样本中目标蛋白结合,配合标记抗体完成信号放大,可实现实验室内对COL1A1的定量分析。该试剂盒适用于科研场景中探究纤维化疾病模型(如肝纤维化、肺纤维化)的分子机制、评估药物干预对胶原代谢的影响,或用于组织工程研究中细胞外基质动态变化的监测,为相关领域的体外实验提供高灵敏度的检测工具。
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别名:COL1A1Collagen alpha-1(I) chain ELISA kit; Alpha-1 type I collagen ELISA kit; Fragment ELISA kit
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缩写:
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Uniprot No.:
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种属:Rattus norvegicus (Rat)
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样本类型:serum, plasma, tissue homogenates
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检测范围:0.156 ng/mL-10 ng/mL
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灵敏度:0.039 ng/mL
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反应时间:1-5h
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样本体积:50-100ul
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检测波长:450 nm
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研究领域:Signal Transduction
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测定原理:quantitative
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测定方法:Sandwich
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数据处理:
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货期:3-5 working days
引用文献
- iTRAQ-based proteomic analysis of combination therapy with taurine, epigallocatechin gallate, and genistein on carbon tetrachloride-induced liver fibrosis in rats. Cao W.et al,Toxicol Lett.,2015
- Lentiviral Vector-Mediated FoxO1 Overexpression Inhibits Extracellular Matrix Protein Secretion Under High Glucose Conditions in Mesangial Cells. Guo F.et al,J Cell Biochem.,2016
相关产品
靶点详情
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功能:Type I collagen is a member of group I collagen (fibrillar forming collagen).
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亚细胞定位:Secreted, extracellular space, extracellular matrix.
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蛋白家族:Fibrillar collagen family
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组织特异性:Forms the fibrils of tendon, ligaments and bones. In bones the fibrils are mineralized with calcium hydroxyapatite.
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数据库链接:
UniGene: Ocu.3445