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N Monoclonal Antibody

Rare Species
  • 中文名称:
    N鼠单克隆抗体
  • 货号:
    CSB-MA33255A0m
  • 规格:
    ¥1320
  • 图片:
    • The Binding Activity of SARS-CoV-2-N Antibody with SARS-CoV-2-N Activity: Measured by its binding ability in a functional ELISA. Immobilized SARS-CoV-2-N (CSB-EP3325GMY) at 2 μg/ml can bind SARS-CoV-2-N Antibody, the EC50 is 13.93 to 25.98 ng/ml.
    • Western Blot
      Positive WB detected in: SARS-CoV-2 nucleocapsid recombinant protein from E. Coli (CSB-EP3325GMY) at 40ng, 20ng, 10ng
      All lanes N antibody at 1:1000
      Secondary
      Goat polyclonal to mouse IgG at 1/50000 dilution
      Predicted band size: 48 KDa
      Observed band size: 55 KDa
  • 其他:

产品详情

  • 产品描述:
    N Monoclonal Antibody(CUSABIO货号:CSB-MA33255A0m)是针对新冠病毒(SARS-CoV-2/2019-nCoV)核衣壳蛋白(N蛋白)研发的高特异性检测工具,适用于病毒基础研究与抗病毒药物开发领域。作为冠状病毒的核心结构蛋白,N蛋白在病毒基因组RNA的包装及宿主免疫逃逸中发挥关键作用,是研究病毒复制机制与宿主相互作用的重要靶点。本产品采用杂交瘤技术制备,具有严格的种属特异性,可精准识别新冠病毒N蛋白抗原表位,经严格验证适用于酶联免疫吸附测定(ELISA)与免疫组织化学(IHC)实验体系。在新冠病毒感染机制研究、疫苗研发效果评估及抗病毒药物筛选等科研场景中,该抗体能够有效实现病毒蛋白的定性及半定量检测,为建立病毒蛋白检测标准、解析感染后免疫应答特征提供可靠工具。其优异的热稳定性与批次间一致性可保障实验数据的可重复性,是新冠病毒基础研究与转化医学领域的重要实验材料。
  • Uniprot No.:
  • 别名:
    N; Nucleoprotein; N; Nucleocapsid protein; NC; Protein N
  • 宿主:
    Mouse
  • 反应种属:
    Human Novel Coronavirus (SARS-CoV-2/ 2019-nCoV)
  • 免疫原:
    Recombinant Human Novel Coronavirus Nucleoprotein (N) (1-419aa) (CSB-EP3325GMY)
  • 免疫原种属:
    Human Novel Coronavirus (SARS-CoV-2/ 2019-nCoV)
  • 标记方式:
    Non-conjugated
  • 克隆类型:
    Monoclonal
  • 抗体亚型:
    IgG1
  • 纯化方式:
    >95%, Protein G purified
  • 克隆号:
    9B2F3-1
  • 浓度:
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式:
    Liquid
  • 应用范围:
    WB, ELISA
  • 推荐稀释比:
    Application Recommended Dilution
    WB 1000-5000
    ELISA 1:1000-1:5000
  • Protocols:
  • 储存条件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

产品评价

靶点详情

  • 功能:
    Packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M. Plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication. May modulate transforming growth factor-beta signaling by binding host smad3.
  • 亚细胞定位:
    Virion. Host cytoplasm.
  • 蛋白家族:
    Betacoronavirus nucleocapsid protein family