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DM1&DM4 Monoclonal Antibody

  • 中文名称:
    DM1&DM4 Monoclonal Antibody
  • 货号:
    CSB-MA989811I0m
  • 规格:
    ¥3000
  • 图片:
    • The Binding Activity of Trastuzumab emtansine (Ado-Trastuzumab emtansine) and Cantuzumab ravtansine (Synonyms:IMGN242) with Anti-DM1&DM4 antibody
      Activity: Measured by its binding ability in a functional ELISA. Immobilized Trastuzumab emtansine (Ado-Trastuzumab emtansine) and Cantuzumab ravtansine (Synonyms:IMGN242) at 2 μg/mL can bind Anti-DM1&DM4 antibody, the EC50 is 2.582 to 5.599 ng/mL and 2.519 to 3.738 ng/mL, respectively.
  • 其他:

产品详情

  • 产品描述:
    DM1/DM4单克隆抗体(CUSABIO货号:CSB-MA989811I0m)是针对美登素衍生物DM1和DM4开发的高特异性科研试剂,专为ELISA检测设计。DM1和DM4作为抗体药物偶联物(ADC)中广泛应用的细胞毒性有效载荷,其精准检测对ADC药物的研发与质量评估具有重要意义。本产品采用杂交瘤技术制备,具有高亲和力和批间稳定性,可特异性识别游离态及偶联态的DM1/DM4分子,适用于人源化样本的分析。在应用场景中,该抗体可助力科研人员开展ADC药物有效载荷的定量分析、偶联工艺优化及药物代谢动力学研究,为新型抗癌药物的作用机制探索和疗效评估提供可靠工具。其优异的交叉反应特性使其能够兼容多种DM1/DM4相关衍生物的检测需求,是生物制药领域进行ADC药物开发、药物载体优化及毒性评估研究的理想选择。通过ELISA平台,研究者可高效完成药物-抗体偶联比(DAR值)测算、药物稳定性测试及生产工艺监控等关键实验环节。
  • 基因名:
    DM1&DM4
  • 别名:
    DM1, DM4, Mertansine, Maytansinoid DM1
  • 宿主:
    Mouse
  • 反应种属:
    Homo sapiens (Human)
  • 免疫原:
    DM4-BSA
  • 标记方式:
    Non-conjugated
  • 克隆类型:
    Monoclonal
  • 抗体亚型:
    IgG2a
  • 纯化方式:
    >95%, Protein G purified
  • 克隆号:
    9G4F1
  • 浓度:
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式:
    Liquid
  • 应用范围:
    ELISA
  • Protocols:
  • 储存条件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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