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  4. ARPC4 Antibody

ARPC4 Antibody

说明书
  • 中文名称：
    ARPC4兔多克隆抗体
  • 货号：
    CSB-PA002130GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    P59998
  • 基因名：
    ARPC4
  • 别名：
    Actin related protein 2/3 complex subunit 4 antibody; Actin related protein 2/3 complex subunit 4 20 kD antibody; Actin related protein 2/3 complex subunit 4 20kDa antibody; Actin related protein 2/3 complex; 20-KD subunit antibody; Actin-related protein 2/3 complex subunit 4 antibody; ARC20 antibody; Arp2/3 complex 20 kDa subunit antibody; Arp2/3 protein complex subunit p20 antibody; ARPC 4 antibody; ARPC4 antibody; ARPC4_HUMAN antibody; MGC13544 antibody; OTTHUMP00000165252 antibody; OTTHUMP00000207520 antibody; p20 Arc antibody; p20-ARC antibody; p20ARC antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human ARPC4
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB
  • Protocols：
    ELISA Protocol
    Western Blotting (WB) Protocol
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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ARPC4 antibodies

ARPC4 Proteins

靶点详情

  • 功能：
    Actin-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA. The Arp2/3 complex promotes homologous recombination (HR) repair in response to DNA damage by promoting nucle...显示更多
  • 基因功能参考文献：
    1. Expression of the ARPC4 severely affects mycobacterium tuberculosis growth and suppresses immunogenic response in murine macrophages PMID: 23894563
    2. we show cell line-specific differences in ARP2/3 complex subunit dependency on cell migratory potential, and suggest ARPC4 to be one of the key members of the ARP2/3 complex in pancreatic cancer. PMID: 23267127
    3. We show that coronin 3 similar to other coronins interacts with the Arp2/3-complex and cofilin indicating that this family in general is involved in regulating Arp2/3-mediated events. PMID: 17274980
  • 亚细胞定位：
    Cytoplasm, cytoskeleton. Cell projection. Nucleus.
  • 蛋白家族：
    ARPC4 family
  • 数据库链接：

    HGNC: 707

    OMIM: 604226

    KEGG: hsa:10093

    STRING: 9606.ENSP00000388169

    UniGene: Hs.323342

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