ARPC4 Antibody

中文名称：

ARPC4兔多克隆抗体
货号：

CSB-PA698728
规格：

￥1100
图片：
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA698728(ARPC4 Antibody) at dilution 1/15, on the right is treated with synthetic peptide. (Original magnification: ×200)

The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using CSB-PA698728(ARPC4 Antibody) at dilution 1/15, on the right is treated with synthetic peptide. (Original magnification: ×200)
其他：

产品详情

Uniprot No.：

P59998
基因名：

ARPC4
别名：

Actin related protein 2/3 complex subunit 4 antibody; Actin related protein 2/3 complex subunit 4 20 kD antibody; Actin related protein 2/3 complex subunit 4 20kDa antibody; Actin related protein 2/3 complex; 20-KD subunit antibody; Actin-related protein 2/3 complex subunit 4 antibody; ARC20 antibody; Arp2/3 complex 20 kDa subunit antibody; Arp2/3 protein complex subunit p20 antibody; ARPC 4 antibody; ARPC4 antibody; ARPC4_HUMAN antibody; MGC13544 antibody; OTTHUMP00000165252 antibody; OTTHUMP00000207520 antibody; p20 Arc antibody; p20-ARC antibody; p20ARC antibody
宿主：

Rabbit
反应种属：

Human,Mouse
免疫原：

Synthetic peptide of Human ARPC4
免疫原种属：

Homo sapiens (Human)
标记方式：

Non-conjugated
抗体亚型：

IgG
纯化方式：

Antigen affinity purification
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
产品提供形式：

Liquid
应用范围：

ELISA,IHC

推荐稀释比：

Application	Recommended Dilution
ELISA	1:1000-1:2000
IHC	1:25-1:100

Protocols：

ELISA Protocol
Immunohistochemistry (IHC) Protocol
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Actin-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA. The Arp2/3 complex promotes homologous recombination (HR) repair in response to DNA damage by promoting nucle...显示更多
基因功能参考文献：
1. Expression of the ARPC4 severely affects mycobacterium tuberculosis growth and suppresses immunogenic response in murine macrophages PMID: 23894563
2. we show cell line-specific differences in ARP2/3 complex subunit dependency on cell migratory potential, and suggest ARPC4 to be one of the key members of the ARP2/3 complex in pancreatic cancer. PMID: 23267127
3. We show that coronin 3 similar to other coronins interacts with the Arp2/3-complex and cofilin indicating that this family in general is involved in regulating Arp2/3-mediated events. PMID: 17274980
亚细胞定位：

Cytoplasm, cytoskeleton. Cell projection. Nucleus.
蛋白家族：

ARPC4 family
数据库链接：

HGNC: 707

OMIM: 604226

KEGG: hsa:10093

STRING: 9606.ENSP00000388169

UniGene: Hs.323342