Ace Antibody

Name: Ace Antibody
Brand: CUSABIO
SKU: CSB-PA001154XA01DLU

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说明书

产品详情

产品名称：

Rabbit anti-Drosophila melanogaster (Fruit fly) Ace Antibody Polyclonal antibody
Uniprot No.：

P07140
基因名：

Ace Antibody
别名：

Acetylcholinesterase (AChE) (EC 3.1.1.7) [Cleaved into: Acetylcholinesterase 16 kDa subunit; Acetylcholinesterase 55 kDa subunit] Ace CG17907
宿主：

Rabbit
反应种属：

Drosophila melanogaster (Fruit fly)
免疫原：

Recombinant Drosophila melanogaster (Fruit fly) Ace protein (44-293aa)
免疫原种属：

Drosophila melanogaster (Fruit fly)
标记方式：

Non-conjugated
克隆类型：

Polyclonal
抗体亚型：

IgG
纯化方式：

>95%, Protein G purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
产品提供形式：

Liquid
应用范围：

ELISA, WB

推荐稀释比：

Application	Recommended Dilution
WB	1:500-1:5000

Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Rapidly hydrolyzes choline released into the synapse. It can hydrolyze butyrylthiocholine.
基因功能参考文献：
1. 1 engineered disulfide bridge, I327C/D375C increased stability to heat denaturation, urea, & organic solvents & provided protease resistance. The new disulfide bridge links the N-terminal domain (first 356 aa) to the C-terminal domain. PMID: 16686937
2. Results provide insights into substrate and product traffic in the Drosophila melanogaster acetylcholinesterase active site gorge. PMID: 18422651
3. kinetic studies show that it affects interactions with peripheral ligands and the entrance of some of the bulkier substrates PMID: 18439026
4. molecular dynamics simulation reveals the insecticidal resistance mechanism of AChE and its mutation PMID: 19263097
亚细胞定位：

Cell junction, synapse. Cell membrane; Lipid-anchor, GPI-anchor. Note=Attached to the membrane of the neuronal cholinergic synapses by a GPI-anchor.
蛋白家族：

Type-B carboxylesterase/lipase family
数据库链接：

KEGG: dme:Dmel_CG17907

STRING: 7227.FBpp0289713

UniGene: Dm.1179