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中文名称：
CHRM5兔多克隆抗体
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货号：
CSB-PA006813
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规格：
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图片：
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其他：
产品详情
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Uniprot No.：
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基因名：
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别名：
CHRM5; Muscarinic acetylcholine receptor M5
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宿主：
Rabbit
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反应种属：
Human
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免疫原：
Synthesized peptide derived from the Internal region of Human mAChR M5.
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免疫原种属：
Homo sapiens (Human)
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标记方式：
Non-conjugated
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抗体亚型：
IgG
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纯化方式：
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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浓度：
It differs from different batches. Please contact us to confirm it.
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保存缓冲液：
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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产品提供形式：
Liquid
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应用范围：
WB, IF, ELISA
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推荐稀释比：
| Application |
Recommended Dilution |
| WB |
1:500-1:2000 |
| IF |
1:200-1:1000 |
| ELISA |
1:40000 |
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Protocols：
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储存条件：
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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货期：
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：
For Research Use Only. Not for use in diagnostic or therapeutic procedures.
靶点详情
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功能：
The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover.
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基因功能参考文献：
- Immunological stimulation leads to M5 mAChR gene expression in lymphocytes. PMID: 12675126
- direct evidence suggesting that the M5 muscarinic receptor gene combined with the alpha7-nicotinic receptor gene may be linked to schizophrenia PMID: 15292665
- mAChR subtypes (m1 to m5)presents in human scleral fibroblasts at both mRNA and protein levels. PMID: 16877267
- the first study to show an association between CHRM5 and substance use in humans PMID: 17608938
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亚细胞定位：
Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein.
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蛋白家族：
G-protein coupled receptor 1 family, Muscarinic acetylcholine receptor subfamily, CHRM5 sub-subfamily
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数据库链接：
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