CHRM5 Antibody

产品详情

产品名称：

Rabbit anti-Homo sapiens (Human) CHRM5 Polyclonal antibody
Uniprot No.：

P08912
基因名：

CHRM5
别名：

CHRM5; Muscarinic acetylcholine receptor M5
宿主：

Rabbit
反应种属：

Human, Mouse
免疫原：

Recombinant Human Muscarinic acetylcholine receptor M5 protein (220-427AA)
免疫原种属：

Homo sapiens (Human)

标记方式：

Non-conjugated

本页面中的产品，CHRM5 Antibody (CSB-PA005385LA01HU)，的标记方式是Non-conjugated。对于CHRM5 Antibody，我们还提供其他标记。见下表：

标记方式	货号	产品名称	应用
HRP	CSB-PA005385LB01HU	CHRM5 Antibody, HRP conjugated	ELISA
FITC	CSB-PA005385LC01HU	CHRM5 Antibody, FITC conjugated
Biotin	CSB-PA005385LD01HU	CHRM5 Antibody, Biotin conjugated	ELISA

克隆类型：

Polyclonal
抗体亚型：

IgG
纯化方式：

>95%, Protein G purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
产品提供形式：

Liquid
应用范围：

ELISA, WB, IHC, IF

推荐稀释比：

Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover.
基因功能参考文献：
1. Immunological stimulation leads to M5 mAChR gene expression in lymphocytes. PMID: 12675126
2. direct evidence suggesting that the M5 muscarinic receptor gene combined with the alpha7-nicotinic receptor gene may be linked to schizophrenia PMID: 15292665
3. mAChR subtypes (m1 to m5)presents in human scleral fibroblasts at both mRNA and protein levels. PMID: 16877267
4. the first study to show an association between CHRM5 and substance use in humans PMID: 17608938
亚细胞定位：

Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein.
蛋白家族：

G-protein coupled receptor 1 family, Muscarinic acetylcholine receptor subfamily, CHRM5 sub-subfamily
数据库链接：

HGNC: 1954

OMIM: 118496

KEGG: hsa:1133

STRING: 9606.ENSP00000372750

UniGene: Hs.584747