DAAM2 Antibody

中文名称：

DAAM2兔多克隆抗体
货号：

CSB-PA774794LA01HU
规格：

￥440
图片：
Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA774794LA01HU at dilution of 1:100

Immunohistochemistry of paraffin-embedded human melanoma using CSB-PA774794LA01HU at dilution of 1:100
其他：

产品详情

产品名称：

Rabbit anti-Homo sapiens (Human) DAAM2 Polyclonal antibody
Uniprot No.：

Q86T65
基因名：

DAAM2
别名：

DAAM2 antibody; DAAM2_HUMAN antibody; Disheveled-associated activator of morphogenesis 2 antibody; dishevelled associated activator of morphogenesis 2 antibody; dJ90A20A.1 antibody; KIAA0381 antibody; MGC90515 antibody; RP1 278E11.1 antibody
宿主：

Rabbit
反应种属：

Human
免疫原：

Recombinant Human Disheveled-associated activator of morphogenesis 2 protein (1-101AA)
免疫原种属：

Homo sapiens (Human)

标记方式：

Non-conjugated

本页面中的产品，DAAM2 Antibody (CSB-PA774794LA01HU)，的标记方式是Non-conjugated。对于DAAM2 Antibody，我们还提供其他标记。见下表：

标记方式	货号	产品名称	应用
HRP	CSB-PA774794LB01HU	DAAM2 Antibody, HRP conjugated	ELISA
FITC	CSB-PA774794LC01HU	DAAM2 Antibody, FITC conjugated
Biotin	CSB-PA774794LD01HU	DAAM2 Antibody, Biotin conjugated	ELISA

克隆类型：

Polyclonal
抗体亚型：

IgG
纯化方式：

>95%, Protein G purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
产品提供形式：

Liquid
应用范围：

ELISA, IHC

推荐稀释比：

Application	Recommended Dilution
IHC	1:20-1:200

Protocols：

ELISA Protocol
Immunohistochemistry (IHC) Protocol
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Key regulator of the Wnt signaling pathway, which is required for various processes during development, such as dorsal patterning, determination of left/right symmetry or myelination in the central nervous system. Acts downstream of Wnt ligands and upstream of beta-catenin (CTNNB1). Required for canonical Wnt signaling pathway during patterning in the dorsal spinal cord by promoting the aggregation of Disheveled (Dvl) complexes, thereby clustering and formation of Wnt receptor signalosomes and potentiating Wnt activity. During dorsal patterning of the spinal cord, inhibits oligode...显示更多
基因功能参考文献：
1. Biochemical analyses demonstrate that Daam2 associates with VHL and facilitates its ubiquitination and degradation. PMID: 29053101
2. Reduction of Daam2 expression occurred with clinical improvement of the patients PMID: 26293489
3. miR-335 regulates the expression of at least five formin family members, three of which are validated, FMNL3, FMN2 and DAAM2. PMID: 24223803
蛋白家族：

Formin homology family
组织特异性：

Expressed in most tissues examined.
数据库链接：

HGNC: 18143

OMIM: 606627

KEGG: hsa:23500

STRING: 9606.ENSP00000274867

UniGene: Hs.357128