DAPP1 Antibody, FITC conjugated
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中文名称：
DAPP1兔多克隆抗体, FITC偶联
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货号：
CSB-PA892478LC01HU
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规格：
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其他：
产品详情
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产品名称：
Rabbit anti-Homo sapiens (Human) DAPP1 Polyclonal antibody
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Uniprot No.：
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基因名：
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别名：
Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide (hDAPP1) (B lymphocyte adapter protein Bam32) (B-cell adapter molecule of 32 kDa), DAPP1, BAM32
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宿主：
Rabbit
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反应种属：
Human
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免疫原：
Recombinant Human Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide protein (1-280aa)
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免疫原种属：
Homo sapiens (Human)
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标记方式：
FITC
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克隆类型：
Polyclonal
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抗体亚型：
IgG
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纯化方式：
>95%, Protein G purified
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浓度：
It differs from different batches. Please contact us to confirm it.
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保存缓冲液：
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
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产品提供形式：
Liquid
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储存条件：
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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货期：
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：
For Research Use Only. Not for use in diagnostic or therapeutic procedures.
靶点详情
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功能：
May act as a B-cell-associated adapter that regulates B-cell antigen receptor (BCR)-signaling downstream of PI3K.
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基因功能参考文献：
- we propose a role for Bam32 in the signaling of MHC class I molecules in professional Ag-presenting DC for the regulation of CD8(+) T cell activation. PMID: 21930970
- novel phosphorylation-dependent function of Bam32 in regulating Rac1 activation and actin remodeling. PMID: 15247305
- BAM32 works downstream of Src family protein tyrosine kinases and functions to link B cell antigen receptor signals with antigen-processing pathways in B cells. PMID: 15494510
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亚细胞定位：
Cytoplasm. Membrane; Peripheral membrane protein. Note=Membrane-associated after cell stimulation leading to its translocation.
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组织特异性：
Highly expressed in placenta and lung, followed by brain, heart, kidney, liver, pancreas and skeletal muscle. Expressed by B-lymphocytes, but not T-lymphocytes or nonhematopoietic cells.
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数据库链接：
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