DTX4 Antibody, FITC conjugated
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中文名称：
DTX4兔多克隆抗体, FITC偶联
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货号：
CSB-PA764784LC01HU
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规格：
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其他：
产品详情
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产品名称：
Rabbit anti-Homo sapiens (Human) DTX4 Polyclonal antibody
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Uniprot No.：
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基因名：
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别名：
Deltex4 antibody; Dtx4 antibody; DTX4_HUMAN antibody; E3 ubiquitin-protein ligase DTX4 antibody; Protein deltex-4 antibody; RING finger protein 155 antibody; RNF155 antibody
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宿主：
Rabbit
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反应种属：
Human
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免疫原：
Recombinant Human E3 ubiquitin-protein ligase DTX4 protein (167-432AA)
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免疫原种属：
Homo sapiens (Human)
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标记方式：
FITC
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克隆类型：
Polyclonal
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抗体亚型：
IgG
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纯化方式：
>95%, Protein G purified
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浓度：
It differs from different batches. Please contact us to confirm it.
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保存缓冲液：
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
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产品提供形式：
Liquid
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储存条件：
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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货期：
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：
For Research Use Only. Not for use in diagnostic or therapeutic procedures.
靶点详情
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功能：
Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Functions as a ubiquitin ligase protein in vivo, mediating 'Lys48'-linked polyubiquitination and promoting degradation of TBK1, targeting to TBK1 requires interaction with NLRP4.
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基因功能参考文献：
- Notch is ligand activated and undergoes DTX4-mediated ubiquitylation and bilateral endocytosis before ADAM10 processing PMID: 28611181
- Our results provide molecular insight into the mechanisms by which NLRP4-DTX4 targets TBK1 for degradation. PMID: 22388039
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亚细胞定位：
Cytoplasm.
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蛋白家族：
Deltex family
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数据库链接：
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