-
中文名称：
DUSP7兔多克隆抗体
-
货号：
CSB-PA613702ESR1HU
-
规格：
-
图片：
-
Western blot
All lanes: Dual specificity protein phosphatase 7 antibody at 10μg/ml + HepG2 whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 45, 41 kDa
Observed band size: 45 kDa
-
Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA613702ESR1HU at dilution of 1:100
-
Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA613702ESR1HU at dilution of 1:100
-
其他：
产品详情
-
产品名称：
Rabbit anti-Homo sapiens (Human) DUSP7 Polyclonal antibody
-
Uniprot No.：
-
基因名：
-
别名：
Dual specificity phosphatase 7 antibody; Dual specificity protein phosphatase 7 antibody; Dual specificity protein phosphatase PYST2 antibody; DUS7_HUMAN antibody; Dusp7 antibody; Jnk Stimulatory Phosphatase 1 antibody; JSP1 antibody; MAP kinase phosphatase X antibody; MKPX antibody; PYST2 antibody
-
宿主：
Rabbit
-
反应种属：
Human
-
免疫原：
Recombinant Human Dual specificity protein phosphatase 7 protein (160-419AA)
-
免疫原种属：
Homo sapiens (Human)
-
标记方式：
Non-conjugated
-
克隆类型：
Polyclonal
-
抗体亚型：
IgG
-
纯化方式：
Antigen Affinity Purified
-
浓度：
It differs from different batches. Please contact us to confirm it.
-
保存缓冲液：
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
-
产品提供形式：
Liquid
-
应用范围：
ELISA, WB, IHC
-
推荐稀释比：
| Application |
Recommended Dilution |
| WB |
1:500-1:2000 |
| IHC |
1:20-1:200 |
-
Protocols：
-
储存条件：
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
货期：
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
-
用途：
For Research Use Only. Not for use in diagnostic or therapeutic procedures.
靶点详情
-
功能：
Dual specificity protein phosphatase. Shows high activity towards MAPK1/ERK2. Also has lower activity towards MAPK14 and MAPK8. In arrested oocytes, plays a role in meiotic resumption. Promotes nuclear envelope breakdown and activation of the CDK1/Cyclin-B complex in oocytes, probably by dephosphorylating and inactivating the conventional protein kinase C (cPKC) isozyme PRKCB. May also inactivate PRKCA and/or PRKCG. Also important in oocytes for normal chromosome alignment on the metaphase plate and progression to anaphase, where it might regulate activity of the spindle-assembly ...
显示更多
-
基因功能参考文献：
- While the low expression level of DUSP7 was restricted to patients with positive rheumatoid factor and anti-citrullinated protein antibodies, the altered expression of CDC25B correlated with the activity of early arthritis. PMID: 28253537
- high levels of Pyst2-L detected in the active state of AML and ALL diseases and in other types of cancer reflect an altered MAPK signaling pathway in such malignant processes PMID: 14576828
- overexpressed in acute myelogenous leukemia PMID: 14674243
-
亚细胞定位：
Cytoplasm.
-
蛋白家族：
Protein-tyrosine phosphatase family, Non-receptor class dual specificity subfamily
-
组织特异性：
Strongly expressed in liver. Expressed at significantly higher levels in malignant hematopoietic cells than in corresponding non-malignant cells.
-
数据库链接：
Most popular with customers
