GNAZ Antibody

文献引用 (1) 说明书

中文名称：

GNAZ兔多克隆抗体
货号：

CSB-PA009601LA01HU
规格：

￥440
图片：
Immunohistochemistry of paraffin-embedded human pancreatic tissue using CSB-PA009601LA01HU at dilution of 1:100

Immunofluorescent analysis of Hela cells using CSB-PA009601LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
其他：

产品详情

产品名称：

Rabbit anti-Homo sapiens (Human) GNAZ Polyclonal antibody
Uniprot No.：

P19086
基因名：

GNAZ
别名：

G(x) alpha chain antibody; GNAZ antibody; GNAZ_HUMAN antibody; Guanine nucleotide-binding protein G(z) subunit alpha antibody; Gz-alpha antibody
宿主：

Rabbit
反应种属：

Human
免疫原：

Recombinant Human Guanine nucleotide-binding protein G(z) subunit alpha protein (3-140AA)
免疫原种属：

Homo sapiens (Human)

标记方式：

Non-conjugated

本页面中的产品，GNAZ Antibody (CSB-PA009601LA01HU)，的标记方式是Non-conjugated。对于GNAZ Antibody，我们还提供其他标记。见下表：

标记方式	货号	产品名称	应用
HRP	CSB-PA009601LB01HU	GNAZ Antibody, HRP conjugated	ELISA
FITC	CSB-PA009601LC01HU	GNAZ Antibody, FITC conjugated
Biotin	CSB-PA009601LD01HU	GNAZ Antibody, Biotin conjugated	ELISA

克隆类型：

Polyclonal
抗体亚型：

IgG
纯化方式：

>95%, Protein G purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
产品提供形式：

Liquid
应用范围：

ELISA, IHC, IF

推荐稀释比：

Application	Recommended Dilution
IHC	1:20-1:200
IF	1:50-1:200

Protocols：

ELISA Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.
基因功能参考文献：
1. GNAZ mutations are associated with melanoma. PMID: 20424519
2. cGMP-phosphodiesterase 6 can be activated by another cancer-retina antigen, transducin, through Wnt5a-Frizzled-2 cascade, which leads to a lowering of cGMP and an increase in intracellular calcium mobilization. PMID: 19946729
3. findings suggest that Galphaz signals may attenuate Rho-induced stimulation of SRF-mediated transcription PMID: 15326221
亚细胞定位：

Membrane; Lipid-anchor.
蛋白家族：

G-alpha family, G(i/o/t/z) subfamily
数据库链接：

HGNC: 4395

OMIM: 139160

KEGG: hsa:2781

STRING: 9606.ENSP00000248996

UniGene: Hs.584760