GPR107 Antibody

中文名称：

GPR107兔多克隆抗体
货号：

CSB-PA736202LA01HU
规格：

￥440
图片：
IHC image of CSB-PA736202LA01HU diluted at 1:400 and staining in paraffin-embedded human brain tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

Immunofluorescence staining of U251 cells with CSB-PA736202LA01HU at 1:133, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
其他：

产品详情

产品名称：

Rabbit anti-Homo sapiens (Human) GPR107 Polyclonal antibody
Uniprot No.：

Q5VW38
基因名：

GPR107
别名：

GPR107; KIAA1624; LUSTR1; Protein GPR107; Lung seven transmembrane receptor 1
宿主：

Rabbit
反应种属：

Human
免疫原：

Recombinant Human Protein GPR107 protein (151-262AA)
免疫原种属：

Homo sapiens (Human)

标记方式：

Non-conjugated

本页面中的产品，GPR107 Antibody (CSB-PA736202LA01HU)，的标记方式是Non-conjugated。对于GPR107 Antibody，我们还提供其他标记。见下表：

标记方式	货号	产品名称	应用
HRP	CSB-PA736202LB01HU	GPR107 Antibody, HRP conjugated	ELISA
FITC	CSB-PA736202LC01HU	GPR107 Antibody, FITC conjugated
Biotin	CSB-PA736202LD01HU	GPR107 Antibody, Biotin conjugated	ELISA

克隆类型：

Polyclonal
抗体亚型：

IgG
纯化方式：

>95%, Protein G purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
产品提供形式：

Liquid
应用范围：

ELISA, IHC, IF

推荐稀释比：

Application	Recommended Dilution
IHC	1:200-1:500
IF	1:50-1:200

Protocols：

ELISA Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Has been proposed to act as a receptor for neuronostatin, a peptide derived from the somatostatin/SST precursor. Involved in blood sugar regulation through the induction of glucagon in response to low glucose.; (Microbial infection) Required for intoxication by Pseudomonas aeruginosa exotoxin A and Campylobacter jejuni CDT. May contribute to the retrograde transport of bacterial toxins, including cholera toxin, from the trans-Golgi network to the endoplasmic reticulum.
基因功能参考文献：
1. The N-terminal region of GPR107 is critical for its biological function. GPR107 might be one of the long-sought receptors that associates with G-proteins to regulate intracellular vesicular transport PMID: 25031321
2. GPR107 is a promising candidate receptor for neuronostatin, and neuronostatin, interacting with GPR107, may play an important role in the central control of cardiovascular function. PMID: 22933024
亚细胞定位：

Cell membrane; Multi-pass membrane protein. Golgi apparatus, trans-Golgi network membrane.
蛋白家族：

LU7TM family
数据库链接：

HGNC: 17830

KEGG: hsa:57720

UniGene: Hs.512461