GPR179 Antibody, Biotin conjugated

产品详情

产品名称：

Rabbit anti-Homo sapiens (Human) GPR179 Polyclonal antibody
Uniprot No.：

Q6PRD1
基因名：

GPR179
别名：

G protein coupled receptor 179 antibody; GP179_HUMAN antibody; GPR158 like 1 antibody; GPR158L1 antibody; GPR179 antibody; Probable G-protein coupled receptor 158-like 1 antibody; Probable G-protein coupled receptor 179 antibody
宿主：

Rabbit
反应种属：

Human
免疫原：

Recombinant Human Probable G-protein coupled receptor 179 protein (1440-1671AA)
免疫原种属：

Homo sapiens (Human)
标记方式：

Biotin
克隆类型：

Polyclonal
抗体亚型：

IgG
纯化方式：

>95%, Protein G purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
产品提供形式：

Liquid
应用范围：

ELISA
Protocols：

ELISA Protocol
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Orphan receptor, involved in vision. Required for signal transduction through retinal depolarizing bipolar cells.
基因功能参考文献：
1. In this study, a novel compound heterozygous mutation, c.[1A>G]; [608G>T] (p.[0?]; p.[W203L]), was identified in the LRIT3 gene of a proband. No mutations were identified in the CABP4 or GPR179 gene. PMID: 27428514
2. We found 1 mutation in GPR179 in congenital stationary night blindness. PMID: 23714322
3. Additional screening with Sanger sequencing of 40 patients identified three other cCSNB patients harboring additional allelic mutations in GPR179. PMID: 22325361
相关疾病：

Night blindness, congenital stationary, 1E (CSNB1E)
亚细胞定位：

Cell membrane; Multi-pass membrane protein.
蛋白家族：

G-protein coupled receptor 3 family
组织特异性：

Expressed in the retina.
数据库链接：

HGNC: 31371

OMIM: 614515

KEGG: hsa:440435

STRING: 9606.ENSP00000345060

UniGene: Hs.462915