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中文名称：
GPR52兔多克隆抗体
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货号：
CSB-PA002787
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规格：
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图片：
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其他：
产品详情
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Uniprot No.：
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基因名：
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别名：
GPR52; G-protein coupled receptor 52
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宿主：
Rabbit
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反应种属：
Human
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免疫原：
Synthesized peptide derived from the C-terminal region of Human GPR52.
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免疫原种属：
Homo sapiens (Human)
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标记方式：
Non-conjugated
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抗体亚型：
IgG
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纯化方式：
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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浓度：
It differs from different batches. Please contact us to confirm it.
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保存缓冲液：
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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产品提供形式：
Liquid
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应用范围：
WB, ELISA
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推荐稀释比：
| Application |
Recommended Dilution |
| WB |
1:500-1:2000 |
| ELISA |
1:10000 |
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Protocols：
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储存条件：
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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货期：
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：
For Research Use Only. Not for use in diagnostic or therapeutic procedures.
靶点详情
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功能：
Gs-coupled receptor activated by antipsychotics reserpine leading to an increase in intracellular cAMP and its internalization. May play a role in locomotor activity through modulation of dopamine, NMDA and ADORA2A-induced locomotor activity. These behavioral changes are accompanied by modulation of the dopamine receptor signaling pathway in striatum. Modulates HTT level via cAMP-dependent but PKA independent mechanisms throught activation of RAB39B that translocates HTT to the endoplasmic reticulum, thus avoiding proteasome degradation.
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基因功能参考文献：
- Data show that G protein-coupled receptor 52 (Gpr52) modulates huntingtin protein (Htt) levels in the striatal cells in vitro and in vivo. PMID: 25738228
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亚细胞定位：
Cell membrane; Multi-pass membrane protein.
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蛋白家族：
G-protein coupled receptor 1 family
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组织特异性：
Expressed in brain, especially in striatum.
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数据库链接：
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