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中文名称：
GRK7兔多克隆抗体
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货号：
CSB-PA002829
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规格：
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图片：
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其他：
产品详情
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Uniprot No.：
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基因名：
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别名：
GRK7 antibody; GPRK7 antibody; Rhodopsin kinase GRK7 antibody; EC 2.7.11.14 antibody; G protein-coupled receptor kinase 7 antibody; G protein-coupled receptor kinase GRK7 antibody
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宿主：
Rabbit
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反应种属：
Human
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免疫原：
Synthesized peptide derived from the Internal region of Human GRK 7.
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免疫原种属：
Homo sapiens (Human)
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标记方式：
Non-conjugated
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抗体亚型：
IgG
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纯化方式：
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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浓度：
It differs from different batches. Please contact us to confirm it.
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保存缓冲液：
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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产品提供形式：
Liquid
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应用范围：
WB, IF, ELISA
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推荐稀释比：
| Application |
Recommended Dilution |
| WB |
1:500-1:2000 |
| IF |
1:200-1:1000 |
| ELISA |
1:20000 |
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Protocols：
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储存条件：
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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货期：
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：
For Research Use Only. Not for use in diagnostic or therapeutic procedures.
靶点详情
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功能：
Retina-specific kinase involved in the shutoff of the photoresponse and adaptation to changing light conditions via cone opsin phosphorylation, including rhodopsin (RHO).
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基因功能参考文献：
- Defects in GRK1 or GRK7 cause patients to suffer from an inability to properly deactivate rhodopsin leading to problems with recovery and dark adaptation. PMID: 22183412
- Phosphorylation of GRK1 and GRK7 by PKA occurs in the dark, when cAMP levels in photoreceptor cells are elevated. PMID: 15946941
- synthesis of 29 of GRK1 or GRK7 partial peptides that cover the entire sequence of GRK1/GRK7, to see which interacts with recoverin. PMID: 18266817
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亚细胞定位：
Membrane; Lipid-anchor.
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蛋白家族：
Protein kinase superfamily, AGC Ser/Thr protein kinase family, GPRK subfamily
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组织特异性：
Retinal cones, outer and inner segments.
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数据库链接：
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