INPP5A Antibody

产品详情

产品名称：

Rabbit anti-Homo sapiens (Human) INPP5A Polyclonal antibody
Uniprot No.：

Q14642
基因名：

INPP5A
别名：

4 antibody; 43 kDa inositol polyphosphate 5-phophatase antibody; 5-trisphosphate 5-phosphatase antibody; 5PTase antibody; CTCL tumor antigen HD-CL-02 antibody; DKFZp434A1721 antibody; I5P1 antibody; I5P1_HUMAN antibody; Inositol polyphosphate 5 phosphatase antibody; inositol polyphosphate-5-phosphatase A antibody; inositol trisphosphate-5-phosphatase antibody; INPP5A antibody; INPP5A inositol polyphosphate-5-phosphatase antibody; InsP3 5-phosphatase antibody; MGC116947 antibody; MGC116949 antibody; Type I inositol-1 antibody; type I inositol-1,4,5-trisphosphate 5-phophatase antibody
宿主：

Rabbit
反应种属：

Human
免疫原：

Recombinant Human Type I inositol 1,4,5-trisphosphate 5-phosphatase protein (1-409AA)
免疫原种属：

Homo sapiens (Human)

标记方式：

Non-conjugated

本页面中的产品，INPP5A Antibody (CSB-PA622780HA01HU)，的标记方式是Non-conjugated。对于INPP5A Antibody，我们还提供其他标记。见下表：

标记方式	货号	产品名称	应用
HRP	CSB-PA622780HB01HU	INPP5A Antibody, HRP conjugated	ELISA
FITC	CSB-PA622780HC01HU	INPP5A Antibody, FITC conjugated
Biotin	CSB-PA622780HD01HU	INPP5A Antibody, Biotin conjugated	ELISA

克隆类型：

Polyclonal
抗体亚型：

IgG
纯化方式：

>95%, Protein G purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
产品提供形式：

Liquid
应用范围：

ELISA, IHC, IF

推荐稀释比：

Application	Recommended Dilution
IHC	1:20-1:200
IF	1:50-1:200

Protocols：

ELISA Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Phosphatase that specifically hydrolyzes the 5-phosphate of inositol 1,4,5-trisphosphate to inositol 1,4-bisphosphate, and inositol 1,3,4,5-tetrasphosphate to inositol 1,3,4-trisphosphate. Plays a crucial role in the survival of cerebellar Purkinje cells.
基因功能参考文献：
1. the overexpression of miR-181a-5p enhanced cell proliferation and invasion and inhibited apoptosis of cervical cancer cells by negatively targeting INPP5A PMID: 28653606
2. The ataxic phenotype and characteristics neurodegeneration of the Inpp5a Gt(OST50073)Lex mouse indicate a crucial role for Inpp5a in purkinje cells survival. PMID: 26051944
3. NPP5Amay play a role in development and progression of cutaneous squamous cell carcinoma tumors PMID: 20876729
亚细胞定位：

Cell membrane; Lipid-anchor. Cell projection, dendrite.
蛋白家族：

Inositol 1,4,5-trisphosphate 5-phosphatase type I family
组织特异性：

Predominantly expressed in heart, brain, and skeletal muscle. In brain; high level in Purkinje cells.
数据库链接：

HGNC: 6076

OMIM: 600106

KEGG: hsa:3632

STRING: 9606.ENSP00000357583

UniGene: Hs.523360