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中文名称：
INPP5A兔多克隆抗体
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货号：
CSB-PA011733GA01HU
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规格：
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其他：
产品详情
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Uniprot No.：
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基因名：
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别名：
4 antibody; 43 kDa inositol polyphosphate 5-phophatase antibody; 5-trisphosphate 5-phosphatase antibody; 5PTase antibody; CTCL tumor antigen HD-CL-02 antibody; DKFZp434A1721 antibody; I5P1 antibody; I5P1_HUMAN antibody; Inositol polyphosphate 5 phosphatase antibody; inositol polyphosphate-5-phosphatase A antibody; inositol trisphosphate-5-phosphatase antibody; INPP5A antibody; INPP5A inositol polyphosphate-5-phosphatase antibody; InsP3 5-phosphatase antibody; MGC116947 antibody; MGC116949 antibody; Type I inositol-1 antibody; type I inositol-1,4,5-trisphosphate 5-phophatase antibody
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宿主：
Rabbit
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反应种属：
Human,Mouse,Rat
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免疫原：
Human INPP5A
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免疫原种属：
Homo sapiens (Human)
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抗体亚型：
IgG
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纯化方式：
Antigen Affinity purified
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浓度：
It differs from different batches. Please contact us to confirm it.
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保存缓冲液：
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
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产品提供形式：
Liquid
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应用范围：
ELISA,WB
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Protocols：
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储存条件：
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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货期：
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：
For Research Use Only. Not for use in diagnostic or therapeutic procedures.
靶点详情
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功能：
Phosphatase that specifically hydrolyzes the 5-phosphate of inositol 1,4,5-trisphosphate to inositol 1,4-bisphosphate, and inositol 1,3,4,5-tetrasphosphate to inositol 1,3,4-trisphosphate. Plays a crucial role in the survival of cerebellar Purkinje cells.
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基因功能参考文献：
- the overexpression of miR-181a-5p enhanced cell proliferation and invasion and inhibited apoptosis of cervical cancer cells by negatively targeting INPP5A PMID: 28653606
- The ataxic phenotype and characteristics neurodegeneration of the Inpp5a Gt(OST50073)Lex mouse indicate a crucial role for Inpp5a in purkinje cells survival. PMID: 26051944
- NPP5Amay play a role in development and progression of cutaneous squamous cell carcinoma tumors PMID: 20876729
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亚细胞定位：
Cell membrane; Lipid-anchor. Cell projection, dendrite.
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蛋白家族：
Inositol 1,4,5-trisphosphate 5-phosphatase type I family
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组织特异性：
Predominantly expressed in heart, brain, and skeletal muscle. In brain; high level in Purkinje cells.
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数据库链接：
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