KCNK17 Antibody

产品详情

Uniprot No.：

Q96T54
基因名：

KCNK17
别名：

KCNK17; TALK2; TASK4; UNQ5816/PRO19634; Potassium channel subfamily K member 17; 2P domain potassium channel Talk-2; Acid-sensitive potassium channel protein TASK-4; TWIK-related acid-sensitive K(+ channel 4; TWIK-related alkaline pH-activated K(+ channel 2; TALK-2
宿主：

Rabbit
反应种属：

Human
免疫原：

Fusion protein of Human KCNK17
免疫原种属：

Homo sapiens (Human)
标记方式：

Non-conjugated
抗体亚型：

IgG
纯化方式：

Antigen affinity purification
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
产品提供形式：

Liquid
应用范围：

ELISA,WB,IHC

推荐稀释比：

Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
Immunohistochemistry (IHC) Protocol
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Outward rectifying potassium channel. Produces rapidly activating and non-inactivating outward rectifier K(+) currents.
基因功能参考文献：
1. The results suggested that heterodimerization of TASK1 and TALK2 provides cells with the ability to make multiple responses to a variety of physiological and pharmacological stimuli. PMID: 29016681
2. The T carrier of an single-nucleotide polymorphism is associated with reduced risk of cerebral hemorrhage in the Chinese population. PMID: 25179130
3. This study demonstrates that Gly88 is a crucial residue for normal TASK-4 gating behavior and that the channel is strongly expressed in the cardiac conduction system. PMID: 24972929
4. The rs10947803 SNP (A allele) in KCNK17 increases the risk of cerebral hemorrhage but not ischemic stroke in the Chinese population. PMID: 23391755
5. The A allele of the rs10947803 variant of KCNK17 was associated with increased risk of IS and increased levels of KCNK17 gene expression. PMID: 19647252
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亚细胞定位：

Membrane; Multi-pass membrane protein.
蛋白家族：

Two pore domain potassium channel (TC 1.A.1.8) family
数据库链接：

HGNC: 14465

OMIM: 607370

KEGG: hsa:89822

STRING: 9606.ENSP00000362328

UniGene: Hs.162282