LRRC8C Antibody

产品详情

Uniprot No.：

Q8TDW0
基因名：

LRRC8C
别名：

AD158 antibody; AI326115 antibody; E430036I04Rik antibody; Factor for adipocyte differentiation 158 antibody; FAD158 antibody; Leucine-rich repeat-containing protein 8C antibody; LRC8C_HUMAN antibody; LRRC8C antibody
宿主：

Rabbit
反应种属：

Human,Mouse,Rat
免疫原：

Human LRRC8C
免疫原种属：

Homo sapiens (Human)
抗体亚型：

IgG
纯化方式：

Antigen Affinity purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
产品提供形式：

Liquid
应用范围：

ELISA,WB,IF
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
Immunofluorescence (IF) Protocol
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Non-essential component of the volume-regulated anion channel (VRAC, also named VSOAC channel), an anion channel required to maintain a constant cell volume in response to extracellular or intracellular osmotic changes. The VRAC channel conducts iodide better than chloride and can also conduct organic osmolytes like taurine. Plays a redundant role in the efflux of amino acids, such as aspartate and glutamate, in response to osmotic stress. The VRAC channel also mediates transport of immunoreactive cyclic dinucleotide GMP-AMP (2'-3'-cGAMP), an immune messenger produced in response ...显示更多
基因功能参考文献：
1. fad158 has a role in regulating adipocyte differentiation PMID: 15184384
亚细胞定位：

Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane.
蛋白家族：

LRRC8 family
组织特异性：

Expressed at highest levels in skeletal muscle, and at moderate levels in heart, lung and peripheral blood leukocytes.
数据库链接：

HGNC: 25075

OMIM: 612889

KEGG: hsa:84230

STRING: 9606.ENSP00000359483

UniGene: Hs.412836