NMUR2 Antibody

中文名称：

NMUR2兔多克隆抗体
货号：

CSB-PA135689
规格：

￥1090
图片：
Western Blot analysis of mouse-brain cells using primary antibody diluted at 1:2000(4°C overnight). Secondary antibody:Goat Anti-rabbit IgG IRDye 800( diluted at 1:5000, 25°C, 1 hour)
其他：

产品详情

Uniprot No.：

Q9GZQ4
基因名：

NMUR2
别名：

NMUR2; NMU2R; TGR1; Neuromedin-U receptor 2; NMU-R2; G-protein coupled receptor FM-4; G-protein coupled receptor TGR-1
宿主：

Rabbit
反应种属：

Human
免疫原：

Synthesized peptide derived from Human NMUR2. at AA range: 1-50
免疫原种属：

Homo sapiens (Human)
标记方式：

Non-conjugated
纯化方式：

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
产品提供形式：

Liquid
应用范围：

WB,ELISA

推荐稀释比：

Application	Recommended Dilution
WB	1:500-2000
ELISA	1:10000-20000

Protocols：

Western Blotting (WB) Protocol
ELISA Protocol
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Receptor for the neuromedin-U and neuromedin-S neuropeptides.
基因功能参考文献：
1. NMU might contribute to progression of NMUR2-positive breast cancer PMID: 28423716
2. polymorphisms in the gene may be useful in identifying women at risk for osteoporosis. PMID: 25871004
3. Study identified a novel NMUR2 splice variant lacking the third exon and able to form heteromeric complexes with NMUR1 and NMUR2 without Neuromedin U (NMU). Its expression can block NMU signaling suppressing then ovarian cancer cells proliferation. PMID: 26317338
4. A cell-based reporter gene assay has been developed and used for the screening of the human NMU2R agonist. PMID: 16781063
亚细胞定位：

Cell membrane; Multi-pass membrane protein.
蛋白家族：

G-protein coupled receptor 1 family
组织特异性：

Predominantly expressed in the CNS, particularly in the medulla oblongata, pontine reticular formation, spinal cord, and thalamus. High level in testis whereas lower levels are present in a variety of peripheral tissues including the gastrointestinal trac
数据库链接：

HGNC: 16454

OMIM: 605108

KEGG: hsa:56923

STRING: 9606.ENSP00000255262

UniGene: Hs.731911