PHKG2 Antibody

产品详情

产品名称：

Rabbit anti-Homo sapiens (Human) PHKG2 Polyclonal antibody
Uniprot No.：

P15735
基因名：

PHKG2
别名：

PHKG2Phosphorylase b kinase gamma catalytic chain antibody; liver/testis isoform antibody; PHK-gamma-LT antibody; PHK-gamma-T antibody; EC 2.7.11.19 antibody; PSK-C3 antibody; Phosphorylase kinase subunit gamma-2 antibody
宿主：

Rabbit
反应种属：

Human
免疫原：

Recombinant Human Phosphorylase b kinase gamma catalytic chain, liver/testis isoform protein (237-406AA)
免疫原种属：

Homo sapiens (Human)
标记方式：

Non-conjugated
克隆类型：

Polyclonal
抗体亚型：

IgG
纯化方式：

Antigen Affinity Purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
产品提供形式：

Liquid
应用范围：

ELISA, WB, IHC

推荐稀释比：

Application	Recommended Dilution
WB	1:1000-1:5000
IHC	1:20-1:200

Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
Immunohistochemistry (IHC) Protocol
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Catalytic subunit of the phosphorylase b kinase (PHK), which mediates the neural and hormonal regulation of glycogen breakdown (glycogenolysis) by phosphorylating and thereby activating glycogen phosphorylase. May regulate glycogeneolysis in the testis. In vitro, phosphorylates PYGM.
基因功能参考文献：
1. These cases add to the current knowledge of clinical variability in patients with PHKG2 mutations. Long term studies, involving follow-up of these patients into adulthood, are needed PMID: 24389071
2. Patients with PHKG2 mutations have a severe hepatic phenotype within the heterogeneous GSD IX disorder. A defect in PHKG2 should be considered in patients with suspected glycogenosis associated with significant liver fibrosis and cirrhosis. PMID: 24326380
3. PHKG2 mutations are associated with Glycogen storage disease type IX PMID: 17689125
相关疾病：

Glycogen storage disease 9C (GSD9C)
蛋白家族：

Protein kinase superfamily, CAMK Ser/Thr protein kinase family
数据库链接：

HGNC: 8931

OMIM: 172471

KEGG: hsa:5261

STRING: 9606.ENSP00000455607

UniGene: Hs.65735