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PPAP2C Antibody

  • 中文名称:
    PPAP2C兔多克隆抗体
  • 货号:
    CSB-PA224357
  • 规格:
    ¥1100
  • 图片:
    • Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane: Mouse trachea tissue, Primary antibody: CSB-PA224357(PPAP2C Antibody) at dilution 1/600, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds
  • 其他:

产品详情

  • Uniprot No.:
  • 基因名:
  • 别名:
    PLPP2; LPP2; PPAP2C; Phospholipid phosphatase 2; Lipid phosphate phosphohydrolase 2; PAP2-gamma; PAP2-G; Phosphatidate phosphohydrolase type 2c; Phosphatidic acid phosphatase 2c; PAP-2c; PAP2c
  • 宿主:
    Rabbit
  • 反应种属:
    Human,Mouse
  • 免疫原:
    Synthetic peptide of Human PPAP2C
  • 免疫原种属:
    Homo sapiens (Human)
  • 标记方式:
    Non-conjugated
  • 抗体亚型:
    IgG
  • 纯化方式:
    Antigen affinity purification
  • 浓度:
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液:
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 产品提供形式:
    Liquid
  • 应用范围:
    ELISA,WB
  • 推荐稀释比:
    Application Recommended Dilution
    ELISA 1:1000-1:2000
    WB 1:200-1:1000
  • Protocols:
  • 储存条件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

产品评价

靶点详情

  • 功能:
    Magnesium-independent phospholipid phosphatase that catalyzes the dephosphorylation of a variety of glycerolipid and sphingolipid phosphate esters including phosphatidate/PA, lysophosphatidate/LPA, sphingosine 1-phosphate/S1P and ceramide 1-phosphate/C1P. Has no apparent extracellular phosphatase activity and therefore most probably acts intracellularly. Also acts on N-oleoyl ethanolamine phosphate/N-(9Z-octadecenoyl)-ethanolamine phosphate, a potential physiological compound. Through dephosphorylation of these bioactive lipid mediators produces new bioactive compounds and may reg...显示更多
  • 基因功能参考文献:
    1. identified a novel and specific role for LPP2 activity and bioactive lipids in regulating cell cycle progression PMID: 16467304
    2. endogenous LPP2 and LPP3 form homo- and hetero-oligomers, which differ in their subcellular localization and which may confer differing spatial regulation of phosphatidic acid and sphingosine 1-phosphate signalling PMID: 18215144
  • 亚细胞定位:
    Membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Early endosome membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.
  • 蛋白家族:
    PA-phosphatase related phosphoesterase family
  • 组织特异性:
    Found mainly in brain, pancreas and placenta.
  • 数据库链接:

    HGNC: 9230

    OMIM: 607126

    KEGG: hsa:8612

    STRING: 9606.ENSP00000329697

    UniGene: Hs.465506