PPP1R12B Antibody

产品详情

Uniprot No.：

O60237
基因名：

PPP1R12B
别名：

PPP1R12B antibody; MYPT2 antibody; Protein phosphatase 1 regulatory subunit 12B antibody; Myosin phosphatase-targeting subunit 2 antibody; Myosin phosphatase target subunit 2 antibody
宿主：

Rabbit
反应种属：

Human,Mouse,Rat
免疫原：

Human PPP1R12B
免疫原种属：

Homo sapiens (Human)
抗体亚型：

IgG
纯化方式：

Antigen Affinity Purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
产品提供形式：

Liquid
应用范围：

ELISA,WB
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Regulates myosin phosphatase activity. Augments Ca(2+) sensitivity of the contractile apparatus.
基因功能参考文献：
1. PPP1R12B is associated with childhood asthma in a Russian population. PMID: 23640410
2. Results describe the characterization and function of MYPT2, a target subunit of myosin phosphatase in heart. PMID: 16431080
3. analysis of the interaction between the coiled coil leucine zipper of cGMP-dependent protein kinase Ialpha and the C terminus of the myosin binding subunit of the myosin light chain phosphatase PMID: 18782776
亚细胞定位：

Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, stress fiber.
组织特异性：

Detected in skeletal muscle, fetal and adult heart, brain, placenta, kidney, spleen, thymus, pancreas and lung. Isoform 3 and isoform 4 are heart specific.
数据库链接：

HGNC: 7619

OMIM: 603768

KEGG: hsa:4660

STRING: 9606.ENSP00000384496

UniGene: Hs.444403