PRKAB2 Antibody

中文名称：

PRKAB2兔多克隆抗体
货号：

CSB-PA652945
规格：

￥1090
图片：
Western blot analysis of 1) 293T, 2) HepG2, 3) Mouse Heart Tissue, 4) Rat Heart Tissue using AMPKβ2 Polyclonal Antibody.
其他：

产品详情

Uniprot No.：

O43741
基因名：

PRKAB2
别名：

5' AMP activated protein kinase beta 2 subunit antibody; 5' AMP activated protein kinase subunit beta 2 antibody; 5''-AMP-activated protein kinase subunit beta-2 antibody; AAKB2_HUMAN antibody; AMP activated protein kinase beta 2 non catalytic subunit antibody; AMPK beta 2 antibody; AMPK beta 2 chain antibody; AMPK subunit beta 2 antibody; AMPK subunit beta-2 antibody; MGC61468 antibody; PRKAB 2 antibody; Prkab2 antibody; Protein kinase AMP activated beta 2 non catalytic subunit antibody
宿主：

Rabbit
反应种属：

Human,Mouse,Rat
免疫原：

Recombinant Protein
免疫原种属：

Homo sapiens (Human)
标记方式：

Non-conjugated
抗体亚型：

IgG
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.
产品提供形式：

Liquid
应用范围：

WB

推荐稀释比：

Application	Recommended Dilution
WB	1:1000-2000

Protocols：

Western Blotting (WB) Protocol
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling t...显示更多
基因功能参考文献：
1. Sumoylation of AMPKbeta2 subunit enhances AMP-activated protein kinase activity. PMID: 23552691
2. results of this study demonistrated that the novel findings that intronic SNPs in the genes coding for the regulatory beta2(PRKAB2) of AMPK are associated with antipsychotic-induced weight gain in schizophrenia or schizoaffective disorder patients PMID: 22305490
3. variants in PRKAB2 are unlikely to contribute to the type 2 diabetes mellitus susceptibility in Pima Indians PMID: 12490143
蛋白家族：

5'-AMP-activated protein kinase beta subunit family
数据库链接：

HGNC: 9379

OMIM: 602741

KEGG: hsa:5565

STRING: 9606.ENSP00000254101

UniGene: Hs.50732