RIC1 Antibody, FITC conjugated
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中文名称：
RIC1兔多克隆抗体, FITC偶联
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货号：
CSB-PA671121LC01HU
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规格：
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其他：
产品详情
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产品名称：
Rabbit anti-Homo sapiens (Human) RIC1 Polyclonal antibody
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Uniprot No.：
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基因名：
RIC1
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别名：
Connexin-43-interacting protein of 150 kDa antibody; Kiaa1432 antibody; Protein RIC1 homolog antibody; RIC1_HUMAN antibody
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宿主：
Rabbit
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反应种属：
Human
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免疫原：
Recombinant Human RAB6A-GEF complex partner protein 1 protein (951-1233AA)
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免疫原种属：
Homo sapiens (Human)
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标记方式：
FITC
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克隆类型：
Polyclonal
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抗体亚型：
IgG
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纯化方式：
>95%, Protein G purified
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浓度：
It differs from different batches. Please contact us to confirm it.
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保存缓冲液：
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
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产品提供形式：
Liquid
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储存条件：
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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货期：
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：
For Research Use Only. Not for use in diagnostic or therapeutic procedures.
靶点详情
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功能：
The RIC1-RGP1 complex acts as a guanine nucleotide exchange factor (GEF), which activates RAB6A by exchanging bound GDP for free GTP, and may thereby be required for efficient fusion of endosome-derived vesicles with the Golgi compartment. The RIC1-RGP1 complex participates in the recycling of mannose-6-phosphate receptors. Required for phosphorylation and localization of GJA1. Is a regulator of procollagen transport and secretion, and is required for correct cartilage morphogenesis and development of the craniofacial skeleton.
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基因功能参考文献：
- KIAA1432 is a novel gene activated by amplification in Small Cell Lung Cancers. PMID: 23716474
- These results suggest that the newly identified domain is essential for the proper phosphorylation and localization of Cx43, and CIP150 is a novel partner protein targeting this domain. PMID: 16112082
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亚细胞定位：
Cytoplasm, cytosol. Membrane.
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蛋白家族：
RIC1 family
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组织特异性：
Present in kidney and various cell lines (at protein level). Widely expressed at low level.
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数据库链接：
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