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中文名称:
SH3GLB2兔多克隆抗体
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货号:
CSB-PA021234GA01HU
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规格:
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其他:
产品详情
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Uniprot No.:
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基因名:
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别名:
Endophilin B2 antibody; Endophilin-B2 antibody; OTTHUMP00000022320 antibody; PP6569 antibody; PP9455 antibody; Retinoid receptor induced gene 1 antibody; RRIG1 antibody; SH3 containing protein SH3GLB2 antibody; SH3 domain GRB2 like endophilin B2 antibody; SH3 domain-containing GRB2-like protein B2 antibody; SH3GLB2 antibody; SHLB2_HUMAN antibody
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宿主:
Rabbit
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反应种属:
Human,Mouse,Rat
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免疫原:
Human SH3GLB2
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免疫原种属:
Homo sapiens (Human)
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抗体亚型:
IgG
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纯化方式:
Antigen Affinity purified
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浓度:
It differs from different batches. Please contact us to confirm it.
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保存缓冲液:
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
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产品提供形式:
Liquid
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应用范围:
ELISA,WB
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Protocols:
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储存条件:
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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货期:
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途:
For Research Use Only. Not for use in diagnostic or therapeutic procedures.
靶点详情
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基因功能参考文献:
- Here the authors report that Endophilin B2, similarly to Endophilin B1, plays an indispensable role in mitochondria sequestration and inner mitochondrial membrane (IMM) protein degradation during mitophagy. PMID: 27112121
- Data (including data from studies in knockout mice) suggest that SH3GLB2 regulates trafficking of endocytic vesicles and autophagosomes to late endosomes or lysosomes; despite having an intracellular localization and tissue distribution similar to endophilin B1, endophilin B2 is dispensable for mitochondrial apoptosis. PMID: 28455444
- the potential importance of the endophilin B2-plectin complex in the biological functions depending on nuclear migration and positioning. PMID: 23921385
- identified a nonmutated HLA-A2-binding epitope in the human ortholog SH3GLB2, which primed T cells from healthy HLA-A2(+) individuals PMID: 18303116
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亚细胞定位:
Cytoplasm.
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蛋白家族:
Endophilin family
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组织特异性:
Detected in skeletal muscle, adipocyte, brain, lung, colon and mammary gland.
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数据库链接:
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