TAOK3 Antibody

产品详情

产品名称：

Rabbit anti-Homo sapiens (Human) TAOK3 Polyclonal antibody
Uniprot No.：

Q9H2K8
基因名：

TAOK3
宿主：

Rabbit
反应种属：

Human
免疫原：

Synthesized peptide derived from internal of Human TAOK3.
免疫原种属：

Homo sapiens (Human)
克隆类型：

Polyclonal
纯化方式：

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度：

It differs from different batches. Please contact us to confirm it.
产品提供形式：

Liquid
应用范围：

ELISA,WB

推荐稀释比：

Application	Recommended Dilution
WB	1:500-1:3000

Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Serine/threonine-protein kinase that acts as a regulator of the p38/MAPK14 stress-activated MAPK cascade and of the MAPK8/JNK cascade. Acts as an activator of the p38/MAPK14 stress-activated MAPK cascade. In response to DNA damage, involved in the G2/M transition DNA damage checkpoint by activating the p38/MAPK14 stress-activated MAPK cascade, probably by mediating phosphorylation of upstream MAP2K3 and MAP2K6 kinases. Inhibits basal activity of MAPK8/JNK cascade and diminishes its activation in response epidermal growth factor (EGF).
基因功能参考文献：
1. Results show that three CpG loci within FYN were hypermethylated in obese individuals, while obesity was associated with lower methylation of CpG loci within PIWIL4 and TAOK3. PMID: 26646899
亚细胞定位：

Cytoplasm. Cell membrane; Peripheral membrane protein. Note=Also localized to the peripheral cell membrane.
蛋白家族：

Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily
组织特异性：

Ubiquitously expressed at a low level, and highly expressed in peripheral blood leukocytes (PBLs), thymus, spleen, kidney, skeletal muscle, heart and liver.
数据库链接：

HGNC: 18133

OMIM: 616711

KEGG: hsa:51347

STRING: 9606.ENSP00000376317

UniGene: Hs.644420