TBKBP1 Antibody, HRP conjugated

产品详情

产品名称：

Rabbit anti-Homo sapiens (Human) TBKBP1 Polyclonal antibody
Uniprot No.：

A7MCY6
基因名：

TBKBP1
别名：

KIAA0775 antibody; ProSAPiP2 antibody; SINTBAD antibody; TANK binding kinase 1 binding protein 1 antibody; TANK-binding kinase 1-binding protein 1 antibody; TBK1 binding protein 1 antibody; TBK1-binding protein 1 antibody; TBKB1_HUMAN antibody; Tbkbp1 antibody
宿主：

Rabbit
反应种属：

Human
免疫原：

Recombinant Human TANK-binding kinase 1-binding protein 1 protein (327-427AA)
免疫原种属：

Homo sapiens (Human)
标记方式：

HRP
克隆类型：

Polyclonal
抗体亚型：

IgG
纯化方式：

>95%, Protein G purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
产品提供形式：

Liquid
应用范围：

ELISA
Protocols：

ELISA Protocol
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Adapter protein which constitutively binds TBK1 and IKBKE playing a role in antiviral innate immunity.
基因功能参考文献：
1. The two selected single nucleotide polymorphisms (SNPs) in TBKBP1 show no relationship with the clinical outcomes. None of the 12 SNPs is related to mSASSS. PMID: 25494292
2. TBKBP1 is associated with the severity of ankylosing spondylitis in the Chinese Han population PMID: 23637848
3. Studies show that three proteins expressed in HEK-293T cells (NAP1, TANK and TBKBP1) interact with TBK1. PMID: 23286385
4. results suggest that efficient signal transduction upon viral infection requires SINTBAD, TANK and NAP1 because they link TBK1 and IKKi to virus-activated signalling cascades PMID: 17568778
组织特异性：

Detected in leukocytes, lung, placenta, small intestine, liver, kidney, spleen, muscle, heart, brain and at low levels in thymus.
数据库链接：

HGNC: 30140

OMIM: 608476

KEGG: hsa:9755

STRING: 9606.ENSP00000354777

UniGene: Hs.94790