TUBB6 Antibody

文献引用 (2) 说明书

产品详情

产品名称：

Rabbit anti-Homo sapiens (Human) TUBB6 Polyclonal antibody
Uniprot No.：

Q9BUF5
基因名：

TUBB6
别名：

tubulin beta-6 chain-like antibody; class V beta-tubulin antibody; HsT1601 antibody; TBB6_HUMAN antibody; TUBB-5 antibody; TUBB6 antibody; Tubulin beta 6 chain antibody; tubulin beta 6 class V antibody; tubulin beta class V antibody; tubulin beta MGC4083 antibody; Tubulin beta-6 antibody; Tubulin beta-6 chain antibody
宿主：

Rabbit
反应种属：

Human
免疫原：

Recombinant Human Tubulin beta-6 chain protein (1-446AA)
免疫原种属：

Homo sapiens (Human)

标记方式：

Non-conjugated

本页面中的产品，TUBB6 Antibody (CSB-PA880105LA01HU)，的标记方式是Non-conjugated。对于TUBB6 Antibody，我们还提供其他标记。见下表：

标记方式	货号	产品名称	应用
HRP	CSB-PA880105LB01HU	TUBB6 Antibody, HRP conjugated	ELISA
FITC	CSB-PA880105LC01HU	TUBB6 Antibody, FITC conjugated
Biotin	CSB-PA880105LD01HU	TUBB6 Antibody, Biotin conjugated	ELISA

克隆类型：

Polyclonal
抗体亚型：

IgG
纯化方式：

>95%, Protein G purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
产品提供形式：

Liquid
应用范围：

ELISA, WB, IHC

推荐稀释比：

Application	Recommended Dilution
WB	1:500-1:2000
IHC	1:20-1:200

Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
Immunohistochemistry (IHC) Protocol
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.
基因功能参考文献：
1. Findings enlarge the spectrum of tubulinopathies and emphasize that mutations of TUBB6 should be considered in patients with congenital non-progressive facial palsy. PMID: 29016863
2. TUBB6 is an inhibitor of pyroptosis. PMID: 24173717
3. Data indicate that leucine-rich repeat kinase 2 (LRRK2) selectively interacts with three beta-tubulin isoforms: TUBB, TUBB4, and TUBB6. PMID: 24275654
4. betaV-tubulin expression is a potentially promising prognostic marker of malignancy. PMID: 22903939
5. in colorectal cancer patients, there was a link between poor survival, the expression of TUBB3/TUBB6, and androgen receptor only in females PMID: 22438565
6. The TUBB6 expression was largely decreased in most tumors. PMID: 20191564
显示更多

收起更多
亚细胞定位：

Cytoplasm, cytoskeleton.
蛋白家族：

Tubulin family
组织特异性：

Ubiquitous. Maximal expression in breast and lung, where it represents around 10% of all beta-tubulins. Largely decreased expression in most cancerous tissues.
数据库链接：

HGNC: 20776

OMIM: 615103

KEGG: hsa:84617

STRING: 9606.ENSP00000318697

UniGene: Hs.193491