WNT8A Antibody, FITC conjugated

产品详情

产品名称：

Rabbit anti-Homo sapiens (Human) WNT8A Polyclonal antibody
Uniprot No.：

Q9H1J5
基因名：

WNT8A
别名：

Protein Wnt-8a antibody; Protein Wnt-8d antibody; wingless type MMTV integration site family, member 8A antibody; WNT 8A antibody; Wnt 8d antibody; wnt8a antibody; WNT8A_HUMAN antibody; WNT8D antibody
宿主：

Rabbit
反应种属：

Human
免疫原：

Recombinant Human Protein Wnt-8a protein (223-309AA)
免疫原种属：

Homo sapiens (Human)
标记方式：

FITC
克隆类型：

Polyclonal
抗体亚型：

IgG
纯化方式：

>95%, Protein G purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
产品提供形式：

Liquid
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Ligand for members of the frizzled family of seven transmembrane receptors. Plays a role in embryonic patterning.
基因功能参考文献：
1. Here, we show that Wnt/planar cell polarity (PCP) autocrine signaling controls the emergence of cytonemes, and that cytonemes subsequently control paracrine Wnt/beta-catenin signal activation. Upon binding of the Wnt family member Wnt8a, the receptor tyrosine kinase Ror2 becomes activated. PMID: 30060804
2. the WNT8A gene is involved in the susceptibility to HSCR, and plays an important role in the occurrence and development of Hirschsprung's disease. PMID: 23836442
3. Expression and regulation of WNT8A mRNA in human tumor cell lines PMID: 11956596
亚细胞定位：

Secreted, extracellular space, extracellular matrix. Secreted.
蛋白家族：

Wnt family
数据库链接：

HGNC: 12788

OMIM: 606360

KEGG: hsa:7478

STRING: 9606.ENSP00000381739

UniGene: Hs.591274