Your Good Partner in Biology Research

中文简体

ACVR2A｜ ACVR2B｜ ALPG｜ CA2｜ CD47｜ CD79A｜ CD79B｜ CLEC9A｜ EPO｜ IL4｜ ITPRIPL1｜ KITLG｜ LTBR｜ TSHR

  1. Home
  2. 抗体
  3. 多克隆抗体
  4. fbpA Antibody, HRP conjugated

fbpA Antibody, HRP conjugated

Rare Species
说明书
  • 中文名称：
    fbpA兔多克隆抗体, HRP偶联
  • 货号：
    CSB-PA18279B0Rb
  • 规格：
    ￥880
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Mycobacterium tuberculosis fbpA Polyclonal antibody
  • Uniprot No.：
    P9WQP3
  • 基因名：
    fbpA
  • 别名：
    fbpA antibody; mpt44 antibody; Rv3804c antibody; MTV026.09cDiacylglycerol acyltransferase/mycolyltransferase Ag85A antibody; DGAT antibody; EC 2.3.1.122 antibody; EC 2.3.1.20 antibody; Acyl-CoA:diacylglycerol acyltransferase antibody; Antigen 85 complex A antibody; 85A antibody; Ag85A antibody; Fibronectin-binding protein A antibody; Fbps A antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Mycobacterium tuberculosis
  • 免疫原：
    Recombinant Mycobacterium tuberculosis Diacylglycerol acyltransferase/mycolyltransferase Ag85A protein (53-331AA)
  • 免疫原种属：
    Mycobacterium tuberculosis
  • 标记方式：
    HRP
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA
  • Protocols：
    ELISA Protocol
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

产品评价

相关产品

fbpA antibodies

靶点详情

  • 功能：
    The antigen 85 proteins (FbpA, FbpB, FbpC) are responsible for the high affinity of mycobacteria for fibronectin, a large adhesive glycoprotein, which facilitates the attachment of M.tuberculosis to murine alveolar macrophages (AMs). They also help to maintain the integrity of the cell wall by catalyzing the transfer of mycolic acids to cell wall arabinogalactan, and through the synthesis of alpha,alpha-trehalose dimycolate (TDM, cord factor). They catalyze the transfer of a mycoloyl residue from one molecule of alpha,alpha-trehalose monomycolate (TMM) to another TMM, leading to t...显示更多
  • 基因功能参考文献：
    1. Ag85A protein can induce strong specific humoral and Th1 type cellular immune responses. PMID: 29727142
    2. A screen for protein-protein interactions reveals a functional link between the virulence-associated lipid transporter LprG and the mycolyltransferase antigen 85A. PMID: 28276676
    3. Using a prime and pull approach, lentivector vaccines expressing Ag85A induce immunogenicity but fail to induce protection against Mycobacterium bovis bacillus Calmette-Guerin challenge in mice. PMID: 26095282
    4. The authors show that the enzyme possesses acyl-CoA:diacylglycerol acyltransferase (DGAT) activity in addition to its well-known function as mycolyltransferase. PMID: 21819455
    5. findings revealed 6 proteins with high-affinity for the fbpA promoter, and 7 with specificity the fbpC promoter PMID: 19959397
    6. analysis of enzymatic hydrolysis of trehalose dimycolate releases free mycolic acids during mycobacterial growth in biofilms PMID: 20375425
    7. In addition to immune recognition of Ag85A whole protein, peptide-mapping studies identified four immunogenic Ag85A peptides, which induced Th-1 immune responses in individual sarcoidosis subjects, suggesting a role in sarcoidosis immunopathogenesis. PMID: 17357846

    收起更多

  • 亚细胞定位：
    Secreted, cell wall. Cytoplasm.
  • 蛋白家族：
    Mycobacterial A85 antigen family
  • 数据库链接：

    KEGG: mtu:Rv3804c

    STRING: 83332.Rv3804c

Most popular with customers

产品中心
特别关注


X