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GPR20 Recombinant Monoclonal Antibody

  • 中文名称:
    GPR20 Recombinant Monoclonal Antibody
  • 货号:
    CSB-RA860774MA1HU
  • 规格:
    ¥1320
  • 图片:
    • The Binding Activity of Macaca fascicularis GPR20 with Anti-GPR20 recombinant antibody
      Activity: Measured by its binding ability in a functional ELISA. Immobilized Macaca fascicularis GPR20(CSB-MP5431MOV ) at 10 μg/mL can bind Anti-GPR20 recombinant antibody. The EC50 is 3.549 - 6.542 ng/mL.
    • The Binding Activity of Human GPR20 with Anti-GPR20 recombinant antibody
      Activity: Measured by its binding ability in a functional ELISA. Immobilized Human GPR20(CSB-MP860774HU) at 10 μg/mL can bind Anti-GPR20 recombinant antibody. The EC50 is 2.431 - 3.239 ng/mL.
    • The purity of GPR20 was greater than 95% as determined by SEC-HPLC
  • 其他:

产品详情

  • 产品描述:
    CSB-RA860774MA1HU GPR20重组单克隆抗体是针对G蛋白偶联受体20(GPR20)开发的高特异性检测工具,适用于ELISA实验体系。该抗体经重组表达技术制备,具有批次间高度一致性,在1:5000至1:50000稀释范围内展现优异的检测灵敏度。GPR20作为孤儿受体在胃肠道间质瘤等肿瘤细胞中呈现异常表达特征,本产品可通过抗原-抗体特异性结合实现对目标蛋白的定量检测,为研究GPR20在细胞信号转导、肿瘤微环境调控中的功能机制提供可靠工具。科研人员可将其应用于体外培养细胞的蛋白表达水平分析、疾病相关分子通路研究及靶向治疗基础研究等实验场景,特别推荐用于胃肠道肿瘤模型构建、受体功能验证等前沿研究领域。
  • Uniprot No.:
  • 基因名:
  • 别名:
    G protein coupled receptor 20 antibody; G-protein coupled receptor 20 antibody; Gpr20 antibody; GPR20_HUMAN antibody
  • 反应种属:
    Human, Macaca fascicularis
  • 免疫原:
    Recombinant Human GPR20 protein
  • 免疫原种属:
    Homo sapiens (Human)
  • 标记方式:
    Non-conjugated
  • 克隆类型:
    Monoclonal
  • 抗体亚型:
    hIgG1
  • 纯化方式:
    Affinity-chromatography
  • 克隆号:
    2C1
  • 浓度:
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式:
    Liquid
  • 应用范围:
    ELISA
  • 推荐稀释比:
    Application Recommended Dilution
    ELISA 1:5000-1:50000
  • Protocols:
  • 储存条件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

产品评价

靶点详情

  • 功能:
    Orphan receptor with constitutive G(i) signaling activity that activate cyclic AMP.
  • 基因功能参考文献:
    1. GPR20 constitutively activates G(i) proteins without ligand stimulation PMID: 18347022
  • 亚细胞定位:
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族:
    G-protein coupled receptor 1 family
  • 组织特异性:
    Ubiquitous with highest levels in intestinal tissues. In the brain detected in thalamus, putamen, and caudate, but not in frontal cortex, pons and hypothalamus.
  • 数据库链接:

    HGNC: 4475

    OMIM: 601908

    KEGG: hsa:2843

    STRING: 9606.ENSP00000366970

    UniGene: Hs.152432