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N Recombinant Monoclonal Antibody

Rare Species
  • 中文名称:
    N重组抗体
  • 货号:
    CSB-RA33255A0GMY
  • 规格:
    ¥2310
  • 图片:
    • The Binding Activity of SARS-CoV-2-N Antibody with SARS-CoV-2-N
      Activity: Measured by its binding ability in a functional ELISA. Immobilized SARS-CoV-2-N (CSB-EP3325GMY) at 2 μg/ml can bind SARS-CoV-2-N Antibody, the EC50 is 6.892 ng/ml.
    • In the Colloidal Gold Immunochromatography Assay detection system, the background of antibody (CSB-RA33255A0GMY) is clean, the detection limit can be as low as 446.4ng/ml (31.25ng/0.07ml), and the sensitivity is very good.
    • ELISA: Immobilize various types of SARS proteins at concentration of 2μg/ml on solid substrate, then react with SARS-CoV-2-N Antibody at concentration of 100μg/ml, 10μg/ml and 1μg/ml. It shows the SARS-CoV-2-N Antibody (CSB-RA33255A0GMY) is specific for SARS-CoV-2-N protein, without any cross-reactivity with NL63-CoV, HCoV-OC43, HCoV-229E or HCoV-HKU1.
  • 其他:

产品详情

  • 产品描述:
    CSB-RA33255A0GMY N Recombinant Monoclonal Antibody是针对病毒核衣壳蛋白(N蛋白)开发的高特异性抗体。N蛋白作为病毒核心结构蛋白,在病毒基因组包装、RNA结合及宿主免疫调控中发挥关键作用,是病原体检测的重要靶标。本抗体采用重组表达技术制备,具有优异的批次一致性和稳定性,经ELISA和胶体金免疫层析(GICA)验证,可精准识别天然构象的N蛋白抗原,其灵敏度在ELISA应用中达到1:10000-1:50000稀释度,在GICA检测中适用于1:500-1:2000稀释范围,满足高分辨率和快速检测需求。该产品适用于病毒抗原的体外定性或半定量分析,可支持病毒学基础研究、免疫学检测试剂开发及抗病毒药物筛选等科研场景。通过严格的交叉反应性验证和亲和力测试,确保其对目标蛋白的特异性识别,且符合ISO质量管理体系标准,适用于要求高重复性的实验体系。本品仅限科研用途,不涉及其他领域应用。
  • Uniprot No.:
  • 别名:
    N; Nucleoprotein; N; Nucleocapsid protein; NC; Protein N
  • 反应种属:
    Human Novel Coronavirus (SARS-CoV-2/ 2019-nCoV)
  • 免疫原:
    Recombinant Human Novel Coronavirus Nucleoprotein (N) (1-419aa)(CSB-EP3325GMY)
  • 免疫原种属:
    Human Novel Coronavirus (SARS-CoV-2/ 2019-nCoV)
  • 标记方式:
    Non-conjugated
  • 克隆类型:
    Monoclonal
  • 抗体亚型:
    Monoclonal mouse (varialbe region)/human (kappa/IgG1 constant)chimeric antibody
  • 纯化方式:
    Affinity-chromatography
  • 克隆号:
    1A6
  • 浓度:
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式:
    Liquid
  • 应用范围:
    ELISA, GICA
  • 推荐稀释比:
    Application Recommended Dilution
    ELISA 1:10000-1:50000
    GICA 1:500-1:2000
  • Protocols:
  • 储存条件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

产品评价

靶点详情

  • 功能:
    Packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M. Plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication. May modulate transforming growth factor-beta signaling by binding host smad3.
  • 亚细胞定位:
    Virion. Host cytoplasm.
  • 蛋白家族:
    Betacoronavirus nucleocapsid protein family