Your Good Partner in Biology Research

中文简体

ACVR2A｜ ACVR2B｜ ALPG｜ CA2｜ CD47｜ CD79A｜ CD79B｜ CLEC9A｜ EPO｜ IL4｜ ITPRIPL1｜ KITLG｜ LTBR｜ TSHR

  1. 首页
  2. 蛋白
  3. 重组蛋白
  4. Recombinant Bovine Heat shock protein HSP 90-beta (HSP90AB1), partial

Recombinant Bovine Heat shock protein HSP 90-beta (HSP90AB1), partial

  • 中文名称：
    牛HSP90AB1重组蛋白
  • 货号：
    CSB-YP751863BO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    牛HSP90AB1重组蛋白
  • 货号：
    CSB-EP751863BO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    牛HSP90AB1重组蛋白
  • 货号：
    CSB-EP751863BO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    牛HSP90AB1重组蛋白
  • 货号：
    CSB-BP751863BO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    牛HSP90AB1重组蛋白
  • 货号：
    CSB-MP751863BO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    HSP90AB1
  • Uniprot No.：
    Q76LV1
  • 别名：
    HSP90AB1; HSPCBHeat shock protein HSP 90-beta
  • 种属：
    Bos taurus (Bovine)
  • 蛋白长度：
    Partial
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a range of client protein classes via its interact...显示更多
  • 基因功能参考文献：
    1. Heat tolerance was assessed in Boran and Nguni cows. Protein levels of HSP90AB1, skin thickness, rectal and skin temperature were higher in the Boran cows than Nguni cows. Breed, age and coat colour did not influence HSP90AB1 concentration. PMID: 29037409
    2. Studied the nucleotide polymorphism within the HSP90AB1 gene (SNP g.4338T>C) in Indian breeds of dairy cattle. PMID: 25153455
    3. Association analysis revealed that the T allele at SNP g.4338T>C of the HSP90AB1 gene improved heat tolerance in cattle. Allele T was 100% in White Lamphun animals, 84% in Mountain cattle, and 18% in Holstein Friesian heifers. PMID: 22008953
    4. This study showed that ubiquitinated ALK5 and phosphorylated heat shock protein 27 specifically accumulate in the cytoskeleton fraction, and ALK1 and ALK5 interact with heat shock protein 90(HSP90). PMID: 21465483
    5. the protective effect exerted by HSP90 on eNOS degradation mediated by calpain represents a novel and critical mechanism that assures the reversibility of the intracellular trafficking and activation of the synthase PMID: 18682401

    收起更多

  • 亚细胞定位：
    Cytoplasm. Melanosome. Nucleus. Secreted. Cell membrane. Dynein axonemal particle.
  • 蛋白家族：
    Heat shock protein 90 family
  • 数据库链接：

    KEGG: bta:767874

    UniGene: Bt.64721

Most popular with customers

产品中心
特别关注


X