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  4. Recombinant Chicken Cofilin-2 (CFL2)

Recombinant Chicken Cofilin-2 (CFL2)

  • 中文名称：
    Recombinant Chicken Cofilin-2(CFL2)
  • 货号：
    CSB-YP005281CH
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    Recombinant Chicken Cofilin-2(CFL2)
  • 货号：
    CSB-EP005281CH
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    Recombinant Chicken Cofilin-2(CFL2)
  • 货号：
    CSB-EP005281CH-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    Recombinant Chicken Cofilin-2(CFL2)
  • 货号：
    CSB-BP005281CH
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    Recombinant Chicken Cofilin-2(CFL2)
  • 货号：
    CSB-MP005281CH
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    CFL2
  • Uniprot No.：
    P21566
  • 别名：
    CFL2; Cofilin-2; Cofilin; muscle isoform
  • 种属：
    Gallus gallus (Chicken)
  • 蛋白长度：
    Full length protein
  • 表达区域：
    1-166
  • 氨基酸序列
    MASGVTVNDE VIKVFNDMKV RKSSTPEEIK KRKKAVLFCL SDDKKQIIVE EAKQILVGDI GDTVEDPYTA FVKLLPLNDC RYALYDATYE TKESKKEDLV FIFWAPESAP LKSKMIYASS KDAIKKKFTG IKHEWQVNGL DDIKDRSTLG EKLGGNVVVS LEGKPL
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Controls reversibly actin polymerization and depolymerization in a pH-sensitive manner. It has the ability to bind G- and F-actin in a 1:1 ratio of cofilin to actin. It is the major component of intranuclear and cytoplasmic actin rods.
  • 基因功能参考文献：
    1. Study reports chicken cofilactin (cofilin-decorated actin filament) 3.8 A resolution cryo-electron microscopy structure which enables to determine the nature of the cofilin-binding-induced conformational transition in the actin subunit. The cofilin-actin interface consists of three distinct parts and cofilin preferentially binds ADP-F-actin versus ATP-actin. PMID: 29749375
    2. Our results suggest that the activity of A3-cofilin and also S3-cofilin can be regulated by PIP(2) in the cytoplasm of muscle cells. PMID: 17823847
  • 亚细胞定位：
    Nucleus matrix. Cytoplasm, cytoskeleton.
  • 蛋白家族：
    Actin-binding proteins ADF family
  • 组织特异性：
    Widely distributed in various tissues.
  • 数据库链接：

    KEGG: gga:423320

    STRING: 9031.ENSGALP00000016266

    UniGene: Gga.19407

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