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  4. Recombinant Chicken Protein phosphatase 1 regulatory subunit 12A (PPP1R12A), partial

Recombinant Chicken Protein phosphatase 1 regulatory subunit 12A (PPP1R12A), partial

  • 中文名称：
    鸡PPP1R12A重组蛋白
  • 货号：
    CSB-YP856184CH
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    鸡PPP1R12A重组蛋白
  • 货号：
    CSB-EP856184CH
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    鸡PPP1R12A重组蛋白
  • 货号：
    CSB-EP856184CH-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    鸡PPP1R12A重组蛋白
  • 货号：
    CSB-BP856184CH
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    鸡PPP1R12A重组蛋白
  • 货号：
    CSB-MP856184CH
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    PPP1R12A
  • Uniprot No.：
    Q90623
  • 别名：
    PPP1R12A; MBS; MYPT1; Protein phosphatase 1 regulatory subunit 12A; 130 kDa myosin-binding subunit of smooth muscle myosin phosphatase; Myosin phosphatase-targeting subunit 1; Myosin phosphatase target subunit 1; PP1M subunit M110; Protein phosphatase myosin-binding subunit
  • 种属：
    Gallus gallus (Chicken)
  • 蛋白长度：
    Partial
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Regulates myosin phosphatase activity.
  • 基因功能参考文献：
    1. crystal structure at 2.7 A resolution of the complex between PP1 and a 34-kDa N-terminal domain of the myosin phosphatase targeting subunit MYPT1. PMID: 15164081
    2. Phosphorylation of both Thr695 and Thr850 by Rho-kinase inhibited activity of the MYPT1 subunit M133. Rates of phosphorylation of the two sites were similar and efficacy of inhibition following phosphorylation was equivalent for each site. PMID: 16297917
  • 亚细胞定位：
    Cytoplasm. Cytoplasm, cytoskeleton, stress fiber.
  • 组织特异性：
    Detected in brain, lung, aorta, heart, gizzard, stomach, oviduct, spleen, kidney and small intestine.
  • 数据库链接：

    KEGG: gga:396020

    STRING: 9031.ENSGALP00000016789

    UniGene: Gga.3159

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