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  4. Recombinant Drosophila melanogaster Protein roadkill (rdx), partial

Recombinant Drosophila melanogaster Protein roadkill (rdx), partial

  • 中文名称：
    黑腹果蝇rdx重组蛋白
  • 货号：
    CSB-YP894217DLU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    黑腹果蝇rdx重组蛋白
  • 货号：
    CSB-EP894217DLU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    黑腹果蝇rdx重组蛋白
  • 货号：
    CSB-EP894217DLU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    黑腹果蝇rdx重组蛋白
  • 货号：
    CSB-BP894217DLU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    黑腹果蝇rdx重组蛋白
  • 货号：
    CSB-MP894217DLU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    rdx
  • Uniprot No.：
    Q9VFP2
  • 别名：
    rdx; HIB; CG12537; Protein roadkill; Hh-induced MATH and BTB domain-containing protein
  • 种属：
    Drosophila melanogaster (Fruit fly)
  • 蛋白长度：
    Partial
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Involved in segment polarity. In complex with gft/CUL3, promotes ubiquitination of ci and its subsequent degradation by the proteasome, which results in hh signaling attenuation. This regulation may be important during eye formation for proper packing of ommatidia into a hexagonal array.
  • 基因功能参考文献：
    1. Dzip1-dependent stabilization of Spop/HIB is evolutionarily conserved and essential for proper regulation of Gli/Ci proteins in the Hh pathway. PMID: 24072710
    2. Rdx blocks entry of Ci-155 into the nucleus in the absence of Su(fu) and Rdx induces the degradation of Ci-155 in the nucleus in the presence of a threshold level of Su(fu) PMID: 23216924
    3. two different mechanisms by which Rdx negatively regulates Ci may play an important role in the fine-tuning of Hh responses PMID: 21179535
    4. a new role for SPOP (rdx) was identified; gene encoding SPOP is a target of segmentation transcription factors; SPOP mediates degradation of Puckered, thereby inducing tumor necrosis factor (TNF)/Eiger-dependent apoptosis PMID: 19164706
  • 亚细胞定位：
    Nucleus.
  • 蛋白家族：
    Tdpoz family
  • 组织特异性：
    Expressed near the anterio-posterior compartment boundary of antenna, leg and wing disks.
  • 数据库链接：

    KEGG: dme:Dmel_CG12537

    STRING: 7227.FBpp0099767

    UniGene: Dm.10784

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