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  4. Recombinant Mouse Plastin-1 (Pls1)

Recombinant Mouse Plastin-1 (Pls1)

  • 中文名称：
    小鼠Pls1重组蛋白
  • 货号：
    CSB-YP663696MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    小鼠Pls1重组蛋白
  • 货号：
    CSB-EP663696MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    小鼠Pls1重组蛋白
  • 货号：
    CSB-EP663696MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    小鼠Pls1重组蛋白
  • 货号：
    CSB-BP663696MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    小鼠Pls1重组蛋白
  • 货号：
    CSB-MP663696MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Pls1
  • Uniprot No.：
    Q3V0K9
  • 别名：
    Pls1; Plastin-1
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-630
  • 氨基酸序列
    MENSTTTISR EELEELQEAF NKIDIDNSGY VSDYELQDLF KEASLPLPGY KVREIVEKIL VVADNNKDGK ISFEEFVSLM QELKSKDISK TFRKIINKRE GITAIGGTSS ISSEGTQHSY SEEEKVAFVN WINKALENDA DCSHLLPMNP NDGSLFKSLA DGILLCKMIN LSEPDTIDER AINKKKLTPF TVSENLNLAL NSASAIGCTV VNIGAQDLKE GKPHLVLGLL WQIIKVGLFA DIEISRNEAL IALLKDGEDL EELMKLSPEE LLLRWVNYHL TNAGWRTINN FSQDIKDSKA YFHLLNQIAP KGDRDDGPAV AIDLSGFNEK NDLKRAGFML QEADKLGCRQ FVTPADVVSG NPKLNLAFVA NLFNTYPCLH KPDNNDIDLN LLEGESKEER TFRNWMNSLG VNPYINHLYS DLADALVIFQ LYEMIRVPVN WSQVNKPPYP ALGGNMKKIE NCNYAVELGK NEAKFSLVGI AGQDLNEGNA TLTLALVWQL MRRYTLKVLS DLGEGEKVTD DIIIKWVNQT LKSANKSTSI SSFKDKSIST SLPVLDLIDA IAPNAVRQEM IKREHLTDED KLNNAKYAIS VARKIGARIY ALPDDLVEVK PKMVMTVFAC LMGKGLNRLK
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Actin-bundling protein. In the inner ear, it is required for stereocilia formation. Mediates liquid packing of actin filaments that is necessary for stereocilia to grow to their proper dimensions.
  • 基因功能参考文献：
    1. we have identified a role for L-plastin in stabilizing long-lived podosomes and in enabling macrophage motility PMID: 27614263
    2. PLS1 biases actin toward liquid packing, which allows stereocilia to grow to a greater diameter. PMID: 27811163
    3. Results show that plastin 1 is dispensable for the initial formation of stereocilia. PMID: 25124451
    4. This study identified LPL as being key to alveolar macrophage development and essential to an effective antipneumococcal response. PMID: 24595139
    5. Plastin 1 accumulates in the terminal web and interacts with keratin 19, possibly contributing to anchoring the rootlets to the keratin network. PMID: 19321664

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  • 亚细胞定位：
    Cytoplasm. Cell projection, stereocilium.
  • 组织特异性：
    In the inner ear, it is expressed in the organ of Corti. Abundant in the utricle (at protein level).
  • 数据库链接：

    KEGG: mmu:102502

    STRING: 10090.ENSMUSP00000091317

    UniGene: Mm.11869

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