Recombinant Mouse ADP/ATP translocase 4 (Slc25a31)
产品详情
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基因名:
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Uniprot No.:
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别名:
Slc25a31; Aac4; Ant4; Sfec; ADP/ATP translocase 4; ADP,ATP carrier protein 4; Adenine nucleotide translocator 4; ANT 4; Solute carrier family 25 member 31; Sperm flagellar energy carrier protein
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种属:
Mus musculus (Mouse)
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蛋白长度:
full length protein
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表达区域:
1-320
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氨基酸序列
MSNESSKKQSSKKALFDPVSFSKDLLAGGVAAAVSKTAVAPIERVKLLLQVQASSKQISP
EARYKGMLDCLVRIPREQGFLSYWRGNLANVIRYFPTQALNFAFKDKYKELFMSGVNKEK
QFWRWFLANLASGGAAGATSLCVVYPLDFARTRLGVDIGKGPEQRQFTGLGDCIMKIAKS
DGLIGLYQGFGVSVQGIIVYRASYFGAYDTVKGLLPKPKETPFLVSFIIAQIVTTCSGIL
SYPFDTVRRRMMMQSGESDRQYKGTIDCFLKIYRHEGVPAFFRGAFSNILRGTGGALVLV
LYDKIKEFLNIDVGGSSSGD
Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
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蛋白标签:
N-terminal 10xHis-tagged
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产品提供形式:
Liquid or Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
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缓冲液:
Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
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储存条件:
Store at -20°C/-80°C upon receipt, aliquoting is necessary for
mutiple use. Avoid repeated freeze-thaw cycles.
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保质期:
The shelf life is related to many factors, storage state,
buffer ingredients, storage temperature and the stability of the protein
itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The
shelf life of lyophilized form is 12 months at -20°C/-80°C.
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货期:
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our
proteins are default shipped with normal blue ice packs, if you
request to ship with dry ice, please communicate with us in advance
and extra fees will be charged.
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注意事项:
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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Datasheet & COA:
Please contact us to get it.
靶点详情
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功能:
ADP:ATP antiporter that mediates import of ADP into the mitochondrial matrix for ATP synthesis, and export of ATP out to fuel the cell. Cycles between the cytoplasmic-open state (c-state) and the matrix-open state (m-state): operates by the alternating access mechanism with a single substrate-binding site intermittently exposed to either the cytosolic (c-state) or matrix (m-state) side of the inner mitochondrial membrane. Specifically required during spermatogenesis, probably to mediate ADP:ATP exchange in spermatocytes. Large ATP supplies from ...
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基因功能参考文献:
- Ant4 is a meiosis-specific gene expressed during both male and female gametogenesis however indispensable only during spermatogenesis and not oogenesis. PMID: 25031318
- Studies indicate that Ant4 was expressed selectively in testis and sperm in adult mammals and was indeed essential for mouse spermatogenesis. PMID: 21858006
- Adenine nucleotide translocase 4 deficiency leads to early meiotic arrest of murine male germ cells. PMID: 19556438
- adenine nucleotide translocase 4 is essential for spermatogenesis PMID: 17681941
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亚细胞定位:
Mitochondrion inner membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein. Cell projection, cilium, flagellum membrane; Multi-pass membrane protein.
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蛋白家族:
Mitochondrial carrier (TC 2.A.29) family
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组织特异性:
Specifically expressed in undifferentiated embryonic stem cells and germ cells. Expression is down-regulated after embryonic stem cells differentiation. In adults, only expressed in developing gametes in testis. In testis, expressed at higher level in spe
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数据库链接:
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