Recombinant Rat Mas-related G-protein coupled receptor member D (Mrgprd)
产品详情
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基因名：
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Uniprot No.：
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别名：
Mrgprd; Mrgd; Mas-related G-protein coupled receptor member D; Beta-alanine receptor; G-protein coupled receptor TGR7
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种属：
Rattus norvegicus (Rat)
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蛋白长度：
full length protein
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表达区域：
1-319
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氨基酸序列
MNYTPYSSPAPGLTISPTMDPVTWVYFSVTFLAMATCVCGIVGNSMVIWLLSFHRVQRSP
FCTYVLNLAVADLLFLLCMASLLSLETGPLLTASTSARVYEGMKRIKYFAYTAGLSLLTA
ISTQRCLSVLFPIWYKCHRPQHLSGVVCGVLWALALLMNFLASFFCVQFWHPDKYQCFKV
DMVFNSLILGIFMPVMVLTSAIIFIRMRKNSLLQRRQPRRLYVVILTSVLVFLTCSLPLG
INWFLLYWVELPQAVRLLYVCSSRFSSSLSSSANPVIYFLVGSQKSHRLQESLGAVLGRA
LQDEPEGRETPSTCTNDGV
Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
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蛋白标签：
N-terminal 10xHis-tagged
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产品提供形式：
Liquid or Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
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缓冲液：
Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
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储存条件：
Store at -20°C/-80°C upon receipt, aliquoting is necessary for
mutiple use. Avoid repeated freeze-thaw cycles.
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保质期：
The shelf life is related to many factors, storage state,
buffer ingredients, storage temperature and the stability of the protein
itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The
shelf life of lyophilized form is 12 months at -20°C/-80°C.
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货期：
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our
proteins are default shipped with normal blue ice packs, if you
request to ship with dry ice, please communicate with us in advance
and extra fees will be charged.
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注意事项：
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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Datasheet & COA：
Please contact us to get it.
靶点详情
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功能：
May regulate nociceptor function and/or development, including the sensation or modulation of pain. Functions as a specific membrane receptor for beta-alanine. The receptor couples with G-protein G(q) and G(i).
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基因功能参考文献：
- Activation of recombinant rat MrgD protein promotes opening of the endogenous calcium-activated chloride channels in Xenopus oocytes. PMID: 24078284
- TGR7 participates in the modulation of neuropathic pain PMID: 15037633
- Interactions between rMrgD and rMrgE modulate the function of rMrgD. PMID: 16282220
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亚细胞定位：
Cell membrane; Multi-pass membrane protein.
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蛋白家族：
G-protein coupled receptor 1 family, Mas subfamily
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组织特异性：
Co-expressed in the small diameter neurons with P2X3 and VR1 in dorsal root ganglia.
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数据库链接：
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