ACP5
ACP5，即抗酒石酸酸性磷酸酶5。别名包括TRACP、TRAP，它是一种由第19号染色体上的基因编码的单一同工酶，是一种结构高度保守的含铁糖蛋白。ACP5主要存在于巨噬细胞、破骨细胞、Gaucher细胞、红细胞、血小板、脾脏毛状细胞以及单核吞噬细胞中，尤其在肺泡巨噬细胞和破骨细胞中含量最丰富。ACP5参与活性氧的生成、正常骨骼发育、成骨细胞调节和巨噬细胞功能，影响一系列途径，并反映骨骼的吸收和破骨细胞活性。研究表明，RANKL可以通过NFATc1和c-Fos增加ACP5的表达，从而加速破骨细胞的生成。ACP5在预防、监测和治疗各种肿瘤以及加速发展人类遗传疾病的有前景的治疗策略中起着至关重要的作用。
热销产品
Recombinant Human Tartrate-resistant acid phosphatase type 5 (ACP5) (CSB-YP001178HU)
验证数据
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
ACP5 Antibodies
ACP5 for Homo sapiens (Human)
| 产品货号 | 产品名称 | 种属反应性 | 应用类型 |
|---|---|---|---|
| CSB-PA001178GA01HU | ACP5 Antibody | Human,Mouse,Rat | ELISA,IHC |
ACP5 Proteins
ACP5 Proteins for Mus musculus (Mouse)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP001178MO CSB-EP001178MO CSB-BP001178MO CSB-MP001178MO CSB-EP001178MO-B |
Recombinant Mouse Tartrate-resistant acid phosphatase type 5 (Acp5) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ACP5 Proteins for Homo sapiens (Human)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-EP001178HU CSB-BP001178HU CSB-MP001178HU CSB-EP001178HU-B |
Recombinant Human Tartrate-resistant acid phosphatase type 5 (ACP5) | E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-YP001178HU | Recombinant Human Tartrate-resistant acid phosphatase type 5 (ACP5) | Yeast |
ACP5 Proteins for Sus scrofa (Pig)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP001178PI CSB-EP001178PI CSB-BP001178PI CSB-MP001178PI CSB-EP001178PI-B |
Recombinant Pig Tartrate-resistant acid phosphatase type 5 (ACP5) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ACP5 Proteins for Oryctolagus cuniculus (Rabbit)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP001178RB CSB-EP001178RB CSB-BP001178RB CSB-MP001178RB CSB-EP001178RB-B |
Recombinant Rabbit Tartrate-resistant acid phosphatase type 5 (ACP5) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ACP5 Proteins for Rattus norvegicus (Rat)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP001178RA CSB-EP001178RA CSB-BP001178RA CSB-MP001178RA CSB-EP001178RA-B |
Recombinant Rat Tartrate-resistant acid phosphatase type 5 (Acp5) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ACP5 ELISA Kit
ACP5 ELISA Kit for Homo sapiens (Human)
| 产品货号 | 产品名称 | 样本类型 | 灵敏度 |
|---|---|---|---|
| CSB-E08490h | Human tartrate-resistant acid phosphatase 5b,TRACP-5b ELISA Kit | serum, plasma, tissue homogenates | 0.078 mIU/mL |
ACP5 ELISA Kit for Mus musculus (Mouse)
| 产品货号 | 产品名称 | 样本类型 | 灵敏度 |
|---|---|---|---|
| CSB-E08492m | Mouse tartrate-resistant acid phosphatase 5b(TRACP-5b) ELISA Kit | serum, plasma, tissue homogenates | 0.02 mIU/mL |
ACP5 ELISA Kit for Oryctolagus cuniculus (Rabbit)
| 产品货号 | 产品名称 | 样本类型 | 灵敏度 |
|---|---|---|---|
| CSB-E15043Rb | Rabbit Tartrate-resistant acid phosphatase 5b (TRAP5b) ELISA Kit | serum, plasma, tissue homogenates | 19.5 μU/mL |
