ASGR1
ASGR1，即肝素结合生长因子相关受体1，别名肝素结合蛋白1（HBP1）、肝素结合生长因子受体（HBGR）。ASGR1是一种主要表达在肝脏的细胞表面受体，由人体细胞自身的基因编码。它的作用机制涉及到与多种配体的结合，包括肝素结合生长因子（HB-EGF）、肝素以及某些脂蛋白等。ASGR1通过与这些配体结合，参与调节细胞增殖、分化和迁移等过程，同时也在脂质代谢和免疫反应中发挥作用。ASGR1在生物学上的意义主要体现在其对肝脏功能的调节作用。它参与了肝脏对脂质的摄取和代谢，特别是低密度脂蛋白（LDL）的清除。此外，ASGR1还与肝脏的再生能力有关，它通过促进肝细胞的增殖来参与肝脏损伤后的修复过程。在病理状态下，ASGR1的功能异常可能与某些肝脏疾病，如非酒精性脂肪肝病（NAFLD）和肝纤维化等有关。因此，ASGR1是肝病研究和治疗中的一个潜在靶点。
热销产品
Recombinant Rat Asialoglycoprotein receptor 1 (Asgr1), partial (CSB-MP002207RA1)
验证数据
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
ASGR1 Antibody (CSB-PA17469A0Rb)
验证数据
Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA17469A0Rb at dilution of 1:100
Immunofluorescent analysis of HepG2 cells using CSB-PA17469A0Rb at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
ASGR1 Antibodies
ASGR1 for Homo sapiens (Human)
| 产品货号 | 产品名称 | 种属反应性 | 应用类型 |
|---|---|---|---|
| CSB-PA17469D0Rb | ASGR1 Antibody, Biotin conjugated | Human | ELISA |
| CSB-PA17469B0Rb | ASGR1 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA002207GA01HU | ASGR1 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA17469C0Rb | ASGR1 Antibody, FITC conjugated | Human | |
| CSB-PA17469A0Rb | ASGR1 Antibody | Human | ELISA, IHC, IF |
| CSB-PA186229 | ASGR1 Antibody | Human | ELISA,WB,IHC |
ASGR1 Proteins
ASGR1 Proteins for Mus musculus (Mouse)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP002207MO | Recombinant Mouse Asialoglycoprotein receptor 1 (Asgr1), partial | Yeast |
| CSB-EP002207MO | Recombinant Mouse Asialoglycoprotein receptor 1 (Asgr1), partial | E.coli |
| CSB-CF002207MO(A4) | Recombinant Mouse Asialoglycoprotein receptor 1 (Asgr1) | in vitro E.coli expression system |
ASGR1 Proteins for Homo sapiens (Human)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP002207HU CSB-BP002207HU CSB-MP002207HU CSB-EP002207HU-B |
Recombinant Human Asialoglycoprotein receptor 1 (ASGR1), partial | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP002207HU | Recombinant Human Asialoglycoprotein receptor 1 (ASGR1), partial | E.coli |
| CSB-CF002207HU | Recombinant Human Asialoglycoprotein receptor 1 (ASGR1) | in vitro E.coli expression system |
ASGR1 Proteins for Rattus norvegicus (Rat)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP002207RA1 CSB-EP002207RA1-B |
Recombinant Rat Asialoglycoprotein receptor 1 (Asgr1), partial | Yeast In Vivo Biotinylation in E.coli |
| CSB-CF002207RA | Recombinant Rat Asialoglycoprotein receptor 1 (Asgr1) | in vitro E.coli expression system |
| CSB-BP002207RA1 | Recombinant Rat Asialoglycoprotein receptor 1 (Asgr1), partial | Baculovirus |
| CSB-MP002207RA1 | Recombinant Rat Asialoglycoprotein receptor 1 (Asgr1), partial | Mammalian cell |
| CSB-EP002207RA1 | Recombinant Rat Asialoglycoprotein receptor 1 (Asgr1), partial | E.coli |
ASGR1 Proteins for Pongo abelii (Sumatran orangutan)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP002207PYX CSB-EP002207PYX CSB-BP002207PYX CSB-MP002207PYX CSB-EP002207PYX-B |
Recombinant Pongo abelii Asialoglycoprotein receptor 1 (ASGR1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ASGR1 ELISA Kit
ASGR1 ELISA Kit for Homo sapiens (Human)
| 产品货号 | 产品名称 | 样本类型 | 灵敏度 |
|---|---|---|---|
| CSB-E09130h | Human asialoglyco protein receptor,ASGPR ELISA Kit | serum, plasma, tissue homogenates | 7.8 ng/mL |
