Your Good Partner in Biology Research

AURKB

AURKB,即极光激酶B,别名AIK2、AIM1、ARK2、AurB、IPL1、STK5、AIM-1、ARK-2、STK-1、STK12、PPP1R48、aurkb-sv1、aurkb-sv2等。它来源于细胞内的基因编码,是极光激酶家族的一员。AURKB在细胞有丝分裂过程中发挥关键作用,通过磷酸化多种蛋白质底物来调控染色体的凝聚、纺锤体的组装以及细胞周期的正确进展。其作用机制确保了细胞分裂的准确性和时序性。在生物学上,AURKB的异常表达与多种癌症的发生和发展密切相关,因此成为癌症研究中的热点。

热销产品

AURKB Antibody (CSB-PA002458EA01HU)

验证数据

CSB-PA002458EA01HU

Immunofluorescence staining of Hela cells with CSB-PA002458EA01HU at 1:166, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).

CSB-PA002458EA01HU

Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA002458EA01HU at dilution of 1:100

CSB-PA002458EA01HU

Immunohistochemistry of paraffin-embedded human spleen tissue using CSB-PA002458EA01HU at dilution of 1:100

AURKB Antibodies

AURKB for Homo sapiens (Human)

AURKB Proteins

AURKB Proteins for Homo sapiens (Human)