AURKB
AURKB，即极光激酶B，别名AIK2、AIM1、ARK2、AurB、IPL1、STK5、AIM-1、ARK-2、STK-1、STK12、PPP1R48、aurkb-sv1、aurkb-sv2等。它来源于细胞内的基因编码，是极光激酶家族的一员。AURKB在细胞有丝分裂过程中发挥关键作用，通过磷酸化多种蛋白质底物来调控染色体的凝聚、纺锤体的组装以及细胞周期的正确进展。其作用机制确保了细胞分裂的准确性和时序性。在生物学上，AURKB的异常表达与多种癌症的发生和发展密切相关，因此成为癌症研究中的热点。
热销产品
AURKB Antibody (CSB-PA002458EA01HU)
验证数据
Immunofluorescence staining of Hela cells with CSB-PA002458EA01HU at 1:166, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA002458EA01HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human spleen tissue using CSB-PA002458EA01HU at dilution of 1:100
AURKB Antibodies
AURKB for Homo sapiens (Human)
| 产品货号 | 产品名称 | 种属反应性 | 应用类型 |
|---|---|---|---|
| CSB-PA002458EA01HU | AURKB Antibody | Human | ELISA, IHC, IF |
| CSB-PA000926 | AURKB Antibody | Human,Mouse,Rat,Monkey | WB, IHC, IF, ELISA |
| CSB-PA000927 | AURKB Antibody | Human,Mouse,Rat | WB, IHC, IF, ELISA |
| CSB-PA070260 | Phospho-AURKB (Y12) Antibody | Human,Mouse,Rat | WB, IHC, ELISA |
| CSB-PA070261 | Phospho-AURKB (T232) Antibody | Human,Mouse,Rat,Monkey | WB, IHC, IF, ELISA |
| CSB-RA230110A0HU | AURKB Recombinant Monoclonal Antibody | Human | ELISA, WB, IHC, IP |
AURKB Proteins
AURKB Proteins for Homo sapiens (Human)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP002458HU CSB-EP002458HU CSB-BP002458HU CSB-MP002458HU CSB-EP002458HU-B |
Recombinant Human Aurora kinase B (AURKB) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
