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AVPR2

AVPR2,即精氨酸加压素受体2,别名V2R、DI1、DIR、NDI、ADHR、DIR3、NDI1。AVPR2由人类AVPR2基因编码,该基因位于X染色体上。AVPR2是一种七跨膜域G蛋白偶联受体(GPCR)超家族的成员,与Gs蛋白耦联,从而刺激腺苷酸环化酶。AVPR2主要在肾脏的远端小管和集合管中表达,其主要功能是响应垂体激素精氨酸加压素(AVP),通过刺激机制使尿液浓缩,维持体内水分平衡。当AVPR2的功能丧失时,会导致肾源性尿崩症(NDI)。AAVPR2的基因表达也与肺组织的发育和肺癌相关。

热销产品

AVPR2 Antibody (CSB-PA002470LA01HU)

验证数据

CSB-PA002470LA01HU

Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA002470LA01HU at dilution of 1:100

CSB-PA002470LA01HU

Immunohistochemistry of paraffin-embedded human ovarian cancer using CSB-PA002470LA01HU at dilution of 1:100

CSB-PA002470LA01HU

Immunofluorescence staining of MCF-7 cells with CSB-PA002470LA01HU at 1:200, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).

AVPR2 Antibodies

AVPR2 for Homo sapiens (Human)

AVPR2 for Pig

AVPR2 Proteins

AVPR2 Proteins for Rattus norvegicus (Rat)

AVPR2 Proteins for Sus scrofa (Pig)

AVPR2 Proteins for Homo sapiens (Human)

AVPR2 Proteins for Bos taurus (Bovine)

AVPR2 Proteins for Mus musculus (Mouse)

AVPR2 Proteins for Canis familiaris (Dog) (Canis lupus familiaris)